Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30228422 | 0.88 | KCNA3 (0.46) | KCNA3MAPTALDH1A1HPGDTSHR | |
| SCHEMBL30228119 | 0.81 | KCNA3 (0.56) | KCNA3ALDH1A1HPGDKDM4EMAOA | |
| SCHEMBL30228405 | 0.80 | CA9 (0.56) | KCNA3MAPTALDH1A1HPGDTSHR | |
| SCHEMBL30228504 | 0.77 | ALDH1A1 (0.52) | KCNA3MAPTALDH1A1HPGDTSHR | |
| SCHEMBL30228654 | 0.75 | KCNA3 (0.44) | KCNA3MAPTALDH1A1HPGDTSHR | |
| SCHEMBL30228352 | 0.71 | KCNA3 (0.55) | KCNA3ALDH1A1HPGDKDM4EMAOA | |
| SCHEMBL30228412 | 0.71 | KCNA3 (0.62) | KCNA3ALDH1A1HPGDKDM4EMAOA | |
| SCHEMBL5691199 | 0.71 | KCNA3 (0.62) | KCNA3ALDH1A1HPGDKDM4EMAOA | |
| SCHEMBL31711138 | 0.71 | MAPT (0.42) | KCNA3MAPTALDH1A1HPGDTSHR | |
| SCHEMBL13908157 | 0.69 | ALDH1A1 (0.53) | ALDH1A1HPGDTSHRMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034346-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |