SCHEMBL3022904

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3143000	0.87	LMNA (0.51)	LMNASMN1; SMN2HTTALDH1A1MEN1
	SCHEMBL3045821	0.86	LMNA (0.48)	LMNASMN1; SMN2HTTALDH1A1MEN1
	SCHEMBL3138696	0.86	ALDH1A1 (0.48)	LMNASMN1; SMN2HTTALDH1A1MEN1
	SCHEMBL3139100	0.85	MEN1 (0.51)	LMNASMN1; SMN2HTTALDH1A1MEN1
	SCHEMBL8211676	0.83	LMNA (0.53)	LMNASMN1; SMN2HTTALDH1A1MEN1
	Hydrochloric Acid SCHEMBL3069882	0.83	ALDH1A1 (0.47)	LMNASMN1; SMN2HTTALDH1A1MEN1
	SCHEMBL14496805	0.83	MEN1 (0.54)	LMNASMN1; SMN2HTTALDH1A1MEN1
	SCHEMBL3138742	0.81	SMN1; SMN2 (0.52)	LMNASMN1; SMN2HTTALDH1A1MEN1
	SCHEMBL3139240	0.81	LMNA (0.55)	LMNASMN1; SMN2HTTALDH1A1MEN1
	SCHEMBL3021311	0.81	LMNA (0.46)	LMNASMN1; SMN2HTTALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.