Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23674500 | 0.70 | LMNA (0.51) | TAAR1LMNACTSLCTSBCTSK | |
| SCHEMBL28175915 | 0.68 | TAAR1 (0.42) | TAAR1LMNACTSLCTSBCTSK | |
| SCHEMBL28176946 | 0.68 | TAAR1 (0.42) | TAAR1LMNACTSLCTSBCTSK | |
| SCHEMBL21626249 | 0.68 | CARM1 (0.43) | LMNACTSLCTSBCTSKHRH3 | |
| SCHEMBL5209947 | 0.67 | TSHR (0.50) | TAAR1LMNACTSLCTSBCTSK | |
| SCHEMBL153049 | 0.67 | LMNA (0.57) | TAAR1LMNATSHRHRH4HRH3 | |
| SCHEMBL306297 | 0.67 | LMNA (0.57) | TAAR1LMNATSHRHRH4HRH3 | |
| SCHEMBL715660 | 0.67 | LMNA (0.57) | TAAR1LMNATSHRHRH4HRH3 | |
| SCHEMBL21908568 | 0.66 | TRPV6 (0.50) | LMNACTSLCTSBCTSKCHRM3 | |
| SCHEMBL19948638 | 0.66 | TRPV6 (0.50) | LMNACTSLCTSBCTSKCHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240336625-A1 | SULFONIMIDAMDE COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2024-10-10 | — | — | US | disclosed |
| EP-4373826-A1 | SULFONIMIDAMDE COMPOUNDS AND USES THEREOF | Genentech, Inc. (US) | 2024-05-29 | — | — | EP | disclosed |
| CN-117677622-A | Sulfonyl imide amide compounds and uses thereof | 基因泰克公司 | 2024-03-08 | — | — | CN | disclosed |
| WO-2023004257-A1 | SULFONIMIDAMDE COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2023-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240336625-A1 | SULFONIMIDAMDE COMPOUNDS AND USES THEREOF | NLRP3, PYCARD, NLRP1 | TAAR1 3381/4885LMNA 1415/4885CTSL 1033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.