SCHEMBL305335

SCHEMBL305335

CC(=O)OC(C)(C)c1ccc(C(C)(C)OC(C)=O)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
ALOX15 P16050 1/20 0.39
GAA P10253 1/20 0.39
CYP2C19 P33261 3/20 0.39
TSHR P16473 2/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP17A1 P05093 1/20 0.38
CYP19A1 P11511 1/20 0.38
MAPK1 P28482 1/20 0.37
HDAC1 Q13547 1/20 0.35
HIF1A Q16665 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
SRD5A2 P31213 1/20 0.34
HPGD P15428 2/20 0.34
HSD17B10 Q99714 2/20 0.34
KDM4E B2RXH2 1/20 0.34
USP2 O75604 1/20 0.34
MAPT P10636 2/20 0.33
CYP3A4 P08684 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4185138 0.93 KIF11 (0.39) ALDH1A1ALOX15GAACYP2C19TSHR
SCHEMBL4459027 0.91 LMNA (0.47) ALDH1A1GAACYP2C19TSHRCYP2D6
SCHEMBL26059369 0.91 ESR1 (0.48) ALDH1A1TSHRHPGDHSD17B10CYP3A4
SCHEMBL25563980 0.89 SMN1; SMN2 (0.44) MAPK1HDAC1SMN1; SMN2HPGDMAPT
SCHEMBL18905281 0.89 CYP2C19 (0.34) ALDH1A1ALOX15GAACYP2C19TSHR
SCHEMBL25563983 0.89 CES2 (0.47) ALDH1A1CYP2C19HDAC1SRD5A2HPGD
SCHEMBL42458 0.89 ALDH1A1 (0.56) ALDH1A1ALOX15CYP2C19TSHRCYP2D6
SCHEMBL17453245 0.88 MAPT (0.50) ALDH1A1ALOX15MAPK1SMN1; SMN2HSD17B10
SCHEMBL4420142 0.88 RXRB (0.41) ALDH1A1ALOX15CYP2C19HDAC1SMN1; SMN2
SCHEMBL21347448 0.86 CYP2C9 (0.50) ALDH1A1CYP2D6CYP2C9MAPK1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 262 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2284203-B1 Method for preparation of polyolefins containing exo-olefin chain ends CHEVRON ORONITE CO (US) 2015-03-04 EP claimed
EP-1572752-B1 POLYMERIZATION PROCESSES EXXONMOBIL CHEM PATENTS INC (US) 2014-08-13 EP claimed
US-8575279-B2 Method for preparation of polyolefins containing exo-olefin chain ends CHEVRON ORONITE COMPANY LLC (US) 2013-11-05 US claimed
US-20130150539-A1 METHOD FOR PREPARATION OF POLYOLEFINS CONTAINING EXO-OLEFIN CHAIN ENDS THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2013-06-13 US claimed
EP-1578806-B1 POLYMERIZATION PROCESSES EXXONMOBIL CHEM PATENTS INC (US) 2013-05-22 EP claimed
US-8383736-B2 Method for preparation of polyolefins containing exo-olefin chain ends CHEVRON ORONITE COMPANY LLC (US) 2013-02-26 US claimed
EP-1572753-B1 POLYMERIZATION PROCESSES EXXONMOBIL CHEM PATENTS INC (US) 2012-06-13 EP claimed
EP-1781715-B1 METHOD FOR PREPARATION OF POLYOLEFINS CONTAINING EXO-OLEFIN CHAIN ENDS CHEVRON ORONITE CO (US) 2011-05-18 EP claimed
EP-1578822-B1 POLYMERS SUBSTANTIALLY FREE OF LONG CHAIN BRANCHING EXXONMOBIL CHEM PATENTS INC (US) 2011-04-06 EP claimed
EP-2284203-A2 Method for preparation of polyolefins containing exo-olefin chain ends Chevron Oronite Company LLC (US) 2011-02-16 EP claimed
EP-1572766-A1 POLYMERS WITH NEW SEQUENCE DISTRIBUTIONS ExxonMobil Chemical Patents Inc. (US) 2005-09-14 EP claimed
EP-1572752-A1 POLYMERIZATION PROCESSES ExxonMobil Chemical Patents Inc. (US) 2005-09-14 EP claimed
EP-1572753-A1 POLYMERIZATION PROCESSES ExxonMobil Chemical Patents Inc. (US) 2005-09-14 EP claimed
US-20050107536-A1 Polymers with new sequence distributions EXXONMOBIL CHEMICAL PATENTS INC. 2005-05-19 US claimed
US-20050101751-A1 Halogenated polymers with new sequence distributions EXXONMOBIL CHEMICAL PATENTS INC. 2005-05-12 US claimed
WO-2004058829-A1 POLYMERIZATION PROCESSES EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2004-07-15 WO claimed
WO-2004058836-A1 POLYMERS WITH NEW SEQUENCE DISTRIBUTIONS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-07-15 WO claimed
WO-2004058828-A1 POLYMERIZATION PROCESSES EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-07-15 WO claimed
WO-2004058827-A1 POLYMERIZATION PROCESSES EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-07-15 WO claimed
WO-2004058835-A1 POLYMERS SUBSTANTIALLY FREE OF LONG CHAIN BRANCHING EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-07-15 WO claimed