Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | FABP7 | O15540 | 2/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL334888 | 1.00 | TSHR (0.40) | TSHRMT-CO2ALOX5FABP7FABP5 | |
| SCHEMBL1279956 | 0.99 | TSHR (0.40) | TSHRMT-CO2ALOX5FABP7FABP5 | |
| SCHEMBL472820 | 0.91 | TSHR (0.41) | TSHRMT-CO2ALOX5FABP7FABP5 | |
| Lithium Ion SCHEMBL1279955 | 0.88 | TSHR (0.39) | TSHRMT-CO2ALOX5FABP7FABP5 | |
| SCHEMBL7714728 | 0.80 | TSHR (0.39) | TSHRFABP7FABP5MAPTCACNA1G | |
| SCHEMBL622854 | 0.78 | FABP5 (0.46) | TSHRFABP7FABP5KMT2A | |
| SCHEMBL30876356 | 0.78 | FABP5 (0.46) | TSHRFABP7FABP5KMT2A | |
| SCHEMBL4605373 | 0.78 | TSHR (0.40) | TSHRMT-CO2ALOX5HTR2A | |
| SCHEMBL23748027 | 0.77 | LMNA (0.36) | TSHRMT-CO2ALOX5MAPTCACNA1G | |
| SCHEMBL618689 | 0.77 | L3MBTL1 (0.54) | TSHRL3MBTL1MAPTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688154-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - Portela & Ca., S.A. (PT) | 2026-02-11 | — | — | EP | disclosed |
| WO-2025023851-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | disclosed |
| EP-4373835-A1 | MACROCYLIC IMMUNOMODULATORS | Bristol-Myers Squibb Company (US) | 2024-05-29 | — | — | EP | disclosed |
| WO-2023004240-A1 | MACROCYLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-01-26 | — | — | WO | disclosed |