SCHEMBL30876356

SCHEMBL30876356

O=C(O)ON1C(=O)CC(C(=O)OCC2c3ccccc3-c3ccccc32)C1=O

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FABP5 Q01469 3/20 0.46
FABP7 O15540 2/20 0.46
KMT2A Q03164 2/20 0.39
TSHR P16473 1/20 0.38
EPHX2 P34913 1/20 0.37
MDM4 O15151 1/20 0.35
TP53 P04637 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CASP3 P42574 2/20 0.34
DPP8 Q6V1X1 1/20 0.34
DPP9 Q86TI2 1/20 0.34
OPRD1 P41143 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL622854 1.00 FABP5 (0.46) FABP5FABP7KMT2ATSHREPHX2
SCHEMBL5663756 0.91 FABP5 (0.43) FABP5FABP7KMT2ATSHREPHX2
SCHEMBL15789977 0.86 FABP5 (0.44) FABP5FABP7KMT2ATSHREPHX2
SCHEMBL29430507 0.84 FABP5 (0.48) FABP5FABP7KMT2ATSHREPHX2
SCHEMBL789074 0.84 FABP5 (0.48) FABP5FABP7KMT2ATSHREPHX2
SCHEMBL7714728 0.81 TSHR (0.39) FABP5FABP7KMT2ATSHREPHX2
SCHEMBL334888 0.78 TSHR (0.40) FABP5FABP7KMT2ATSHR
SCHEMBL30229708 0.78 TSHR (0.40) FABP5FABP7KMT2ATSHR
SCHEMBL1279956 0.77 TSHR (0.40) FABP5FABP7KMT2ATSHR
SCHEMBL23748027 0.74 LMNA (0.36) KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4477687-A1 IMMUNOLOGICALLY INACTIVE POLY(ETHYLENE GLYCOL) POLYMER DERIVATIVES AND BIOCONJUGATES THEREOF FOR USE AS ALTERNATIVE IN PEGYLATED THERAPEUTICS, PROCESSES FOR THEIR PREPARATION AND THEIR USE Johannes Gutenberg-Universität Mainz (DE) 2024-12-18 EP disclosed
EP-4361198-A1 POLY(ETHYLENE GLYCOL) HAVING C2-ALKYLOXYMETHYL SIDE CHAINS, C3-ALKYLOXYMETHYL SIDE CHAINS OR BOTH, BIOCONJUGATES THEREOF, PROCESS FOR ITS PREPARATION AND ITS USE Johannes Gutenberg-Universität Mainz (DE) 2024-05-01 EP disclosed