SCHEMBL334888

SCHEMBL334888

O=C(O)ON1C(=O)CC(CC2c3ccccc3-c3ccccc32)C1=O

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.40
MT-CO2 P00403 1/20 0.36
ALOX5 P09917 1/20 0.36
FABP7 O15540 2/20 0.34
FABP5 Q01469 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
MAPT P10636 1/20 0.33
CACNA1G O43497 1/20 0.33
EDNRB P24530 1/20 0.33
EDNRA P25101 1/20 0.33
HTR2A P28223 1/20 0.33
KMT2A Q03164 2/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30229708 1.00 TSHR (0.40) TSHRMT-CO2ALOX5FABP7FABP5
SCHEMBL1279956 0.99 TSHR (0.40) TSHRMT-CO2ALOX5FABP7FABP5
SCHEMBL472820 0.91 TSHR (0.41) TSHRMT-CO2ALOX5FABP7FABP5
Lithium Ion SCHEMBL1279955 0.88 TSHR (0.39) TSHRMT-CO2ALOX5FABP7FABP5
SCHEMBL7714728 0.80 TSHR (0.39) TSHRFABP7FABP5MAPTCACNA1G
SCHEMBL622854 0.78 FABP5 (0.46) TSHRFABP7FABP5KMT2A
SCHEMBL30876356 0.78 FABP5 (0.46) TSHRFABP7FABP5KMT2A
SCHEMBL4605373 0.78 TSHR (0.40) TSHRMT-CO2ALOX5HTR2A
SCHEMBL23748027 0.77 LMNA (0.36) TSHRMT-CO2ALOX5MAPTCACNA1G
SCHEMBL618689 0.77 L3MBTL1 (0.54) TSHRL3MBTL1MAPTKMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 638 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010814-A (2S, 4R) -1-Fmoc-4- (O-allyloxycarbonyl methyl) -proline and synthesis method thereof 杭州澳赛诺医药技术有限公司 2026-05-12 CN claimed
CN-119930797-A Preparation method and application of S-adenosyl homocysteine artificial complete antigen 珠海科技学院 2025-05-06 CN claimed
CN-119875106-A Pegylated calixarene compound as well as preparation method and application thereof 中国药科大学 2025-04-25 CN claimed
CN-119350432-B Preparation method of N- (N- (9-fluorenylmethoxycarbonyl) -L-isoleucyl) -2-aminoisobutyric acid 安徽昊帆生物有限公司 2025-04-25 CN claimed
CN-119708112-A Synthesis method of natural product of Ribes isosteroid alkaloid 华东师范大学 2025-03-28 CN claimed
CN-119708111-A Method for synthesizing cyclopamine from veratramine 华东师范大学 2025-03-28 CN claimed
CN-119613293-A Method suitable for industrial production of Fmoc-Thr (tBu) -OH 成都市科隆化学品有限公司 2025-03-14 CN claimed
CN-119504501-A Efficient preparation method of Fmoc-Lys (Boc) -OH 成都市科隆化学品有限公司 2025-02-25 CN claimed
CN-119504503-A Method for efficiently preparing Fmoc-Dap-OH 成都市科隆化学品有限公司 2025-02-25 CN claimed
CN-119350220-A Method for preparing N-alpha-fluorenylmethoxycarbonyl-N-in-t-butoxycarbonyl-L-tryptophan 富乐马鸿凯(大连)医药有限公司 2025-01-24 CN claimed
EP-1158589-A1 SECONDARY LITHIUM BATTERY, NEGATIVE ELECTRODE FOR SECONDARY LITHIUM BATTERY, AND PROCESS FOR PRODUCING THE NEGATIVE ELECTRODE FUJITSU LIMITED (JP) 2001-11-28 EP claimed
US-20010031396-A1 Lithium secondary battery, anode for lithium secondary battery, and method for manufacturing the anode FUJITSU LIMITED (JP) 2001-10-18 US claimed
US-6258931-B1 SYNTHESIZING DEOXYHYPUSINE DERIVATIVE BY USING ESTER OF DIPROTECTED LYSINE, DEBLOCKING ONE NITROGEN, CONDENSING WITH 3-CYANOPROPANAL, REDUCING TO A TRIAMINE, PROTECTING FREE AMINO GROUPS, DEBLOCKING AGAIN, AND ACYLATING THE FREE AMINO GROUP UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2001-07-10 US claimed
US-6248866-B1 MULTISTEP PROCESS FOR PRODUCTION OF PROTECTED HYPUSINE STARTING FROM PROTECTED, ESTERIFIED LYSINE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED 2001-06-19 US claimed
EP-1032585-A1 DEOXYHYPUSINE REAGENT AND PEPTIDES UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2000-09-06 EP claimed
EP-1032411-A1 HYPUSINE REAGENT FOR PEPTIDE SYNTHESIS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2000-09-06 EP claimed
WO-2000011020-A9 DEOXYHYPUSINE REAGENT AND PEPTIDES UNIV FLORIDA (US) 2000-08-10 WO claimed
WO-2000011020-A1 DEOXYHYPUSINE REAGENT AND PEPTIDES UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2000-03-02 WO claimed
US-5973113-A Hypusine reagent for peptide synthesis UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 1999-10-26 US claimed
WO-1999022757-A1 HYPUSINE REAGENT FOR PEPTIDE SYNTHESIS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 1999-05-14 WO claimed