SCHEMBL302337

SCHEMBL302337

Cc1cccc(C(=O)OCC(C)C)c1C(=O)OCC(C)C

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.67
TSHR P16473 2/20 0.67
KMT2A Q03164 4/20 0.50
MAPT P10636 3/20 0.50
MEN1 O00255 3/20 0.50
TP53 P04637 1/20 0.50
NPY1R P25929 1/20 0.50
NPY2R P49146 1/20 0.50
ATM Q13315 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
ADRB2 P07550 4/20 0.49
ADRB1 P08588 4/20 0.49
ADRB3 P13945 4/20 0.49
SMN1; SMN2 Q16637 2/20 0.45
HTT P42858 2/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
KDM4E B2RXH2 1/20 0.45
CA2 P00918 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4627359 0.95 ALDH1A1 (0.61) ALDH1A1TSHRKMT2AMAPTMEN1
SCHEMBL27553264 0.92 ALDH1A1 (0.61) ALDH1A1TSHRKMT2AMAPTMEN1
Ammonia Solution, Strong SCHEMBL28127857 0.91 ALDH1A1 (0.59) ALDH1A1TSHRKMT2AMAPTMEN1
SCHEMBL7059492 0.90 ALDH1A1 (0.76) ALDH1A1TSHRKMT2AMAPTMEN1
SCHEMBL4843311 0.90 ALDH1A1 (0.59) ALDH1A1TSHRKMT2AMAPTMEN1
SCHEMBL4627967 0.89 TSHR (0.56) ALDH1A1TSHRKMT2AMAPTMEN1
SCHEMBL6057357 0.85 ALDH1A1 (0.79) ALDH1A1TSHRKMT2AMAPTMEN1
SCHEMBL21113716 0.84 TSHR (0.46) ALDH1A1TSHRKMT2AMAPTMEN1
SCHEMBL5695932 0.84 ALDH1A1 (0.67) ALDH1A1TSHRKMT2AMAPTMEN1
SCHEMBL6579635 0.84 ALDH1A1 (0.67) ALDH1A1TSHRKMT2AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3517555-B1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2024-11-27 EP claimed
EP-3517553-B1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2023-11-08 EP claimed
US-11325994-B2 Catalyst component for olefin polymerization, catalyst, and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2022-05-10 US claimed
CN-107868147-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-09-15 CN claimed
CN-107868149-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-07-24 CN claimed
US-10662268-B2 Catalyst component for olefin polymerization, catalyst, and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2020-05-26 US claimed
US-20190256623-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST, AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-08-22 US claimed
EP-3517555-A1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF China Petroleum&Chemical Corporation (CN) 2019-07-31 EP claimed
EP-3517553-A1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF China Petroleum&Chemical Corporation (CN) 2019-07-31 EP claimed
US-20190211119-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST, AND USE THEREOF BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-07-11 US claimed
CN-104371051-B Catalyst for polymerizing butene-1, preparation and application thereof 中国石油天然气股份有限公司 2017-05-10 CN claimed
EP-3517555-B1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2024-11-27 EP disclosed
CN-117924544-A Solid catalyst component for olefin polymerization, preparation method thereof, catalyst and application thereof in olefin polymerization 中国石油化工股份有限公司 2024-04-26 CN disclosed
CN-117924542-A Solid catalyst component for olefin polymerization, preparation method, catalyst and application thereof 中国石油化工股份有限公司 2024-04-26 CN disclosed
EP-3517553-B1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2023-11-08 EP disclosed
US-6670497-B2 Dialkyl (at least one of which is a C4-8 tertiary alkyl) ester of an alkyl- or halo-substituted phthalic acid; used in an olefin polymerization catalyst TOHO TITANIUM CO., LTD. (JP) 2003-12-30 US disclosed
US-20030130109-A1 Solid catalyst component and catalyst for olefins polymerization TOHO TITANIUM CO., LTD (JP) 2003-07-10 US disclosed
US-20030036594-A1 Phthalic diester derivatives and electron donors TOHO TITANIUM CO., LTD. (JP) 2003-02-20 US disclosed
EP-1209172-A1 SOLID CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION Toho Titanium Co., Ltd. (JP) 2002-05-29 EP disclosed
EP-1188739-A1 PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS TOHO TITANIUM CO., LTD. (JP) 2002-03-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030036594-A1 Phthalic diester derivatives and electron donors HPD, ETFA, PPOX ALDH1A1 725/4885TSHR 4817/4885KMT2A 3313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.