Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.67 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.64 |
| ▸ | PPARG | P37231 | 7/20 | 0.64 |
| ▸ | PPARD | Q03181 | 7/20 | 0.64 |
| ▸ | PPARA | Q07869 | 7/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.64 |
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.64 |
| ▸ | FABP4 | P15090 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | TLR2 | O60603 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.64 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | ESR1 | P03372 | 1/20 | 0.64 |
| ▸ | PDE4A | P27815 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valeric Acid SCHEMBL28239218 | 1.00 | AKR1B1 (0.67) | AKR1B1GPR84PPARGPPARDPPARA | |
| Valeric Acid SCHEMBL15261405 | 1.00 | AKR1B1 (0.67) | AKR1B1GPR84PPARGPPARDPPARA | |
| Valeric Acid SCHEMBL29009717 | 0.97 | AKR1B1 (0.64) | AKR1B1GPR84PPARGPPARDPPARA | |
| Valeric Acid SCHEMBL29199834 | 0.95 | AKR1B1 (0.61) | AKR1B1GPR84PPARGPPARDPPARA | |
| Hexanoate SCHEMBL12817011 | 0.92 | AKR1B1 (0.80) | AKR1B1GPR84PPARGPPARDPPARA | |
| Hexanoate SCHEMBL12817527 | 0.92 | AKR1B1 (0.80) | AKR1B1GPR84PPARGPPARDPPARA | |
| Hexanoate SCHEMBL27603848 | 0.92 | AKR1B1 (0.80) | AKR1B1GPR84PPARGPPARDPPARA | |
| Hexanoate SCHEMBL15260773 | 0.92 | AKR1B1 (0.80) | AKR1B1GPR84PPARGPPARDPPARA | |
| Stearic Acid SCHEMBL2199497 | 0.90 | GPR84 (0.81) | AKR1B1GPR84PPARGPPARDPPARA | |
| Octanoic Acid SCHEMBL9421271 | 0.90 | GPR84 (0.81) | AKR1B1GPR84PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230047296-A1 | Nrf2 REGULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230047296-A1 | Nrf2 REGULATORS | NFE2L2, KEAP1, NQO1 | AKR1B1 360/4885GPR84 1158/4885PPARG 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.