Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 15/20 | 0.64 |
| ▸ | ROCK2 | O75116 | 14/20 | 0.64 |
| ▸ | PRKG1 | Q13976 | 7/20 | 0.64 |
| ▸ | PRKACA | P17612 | 6/20 | 0.64 |
| ▸ | GSK3A | P49840 | 5/20 | 0.64 |
| ▸ | GSK3B | P49841 | 5/20 | 0.64 |
| ▸ | PRKX | P51817 | 5/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.64 |
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.64 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.64 |
| ▸ | PKN2 | Q16513 | 4/20 | 0.64 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.64 |
| ▸ | SGK2 | Q9HBY8 | 4/20 | 0.64 |
| ▸ | RPS6KA5 | O75582 | 3/20 | 0.64 |
| ▸ | CDK2 | P24941 | 3/20 | 0.64 |
| ▸ | AKT2 | P31751 | 3/20 | 0.64 |
| ▸ | PRKG2 | Q13237 | 3/20 | 0.64 |
| ▸ | CDC42BPA | Q5VT25 | 3/20 | 0.64 |
| ▸ | HIPK4 | Q8NE63 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3032715 | 1.00 | ROCK1 (0.64) | ROCK1ROCK2PRKG1PRKACAGSK3A | |
| SCHEMBL2408586 | 0.86 | CA1 (0.59) | ROCK1ROCK2PRKG1PRKACAGSK3A | |
| SCHEMBL2407090 | 0.86 | CA1 (0.59) | ROCK1ROCK2PRKG1PRKACAGSK3A | |
| SCHEMBL2412518 | 0.86 | GPR139 (0.65) | ROCK1ROCK2PRKG1PRKACAGSK3A | |
| SCHEMBL3036088 | 0.84 | ALDH1A1 (0.64) | ROCK1ROCK2PRKG1PRKACAGSK3A | |
| SCHEMBL29742390 | 0.83 | ROCK1 (0.71) | ROCK1ROCK2PRKG1PRKACAGSK3A | |
| SCHEMBL28642442 | 0.83 | ROCK1 (0.71) | ROCK1ROCK2PRKG1PRKACAGSK3A | |
| SCHEMBL5007649 | 0.82 | ROCK2 (0.63) | ROCK1ROCK2PRKG1PRKACAGSK3A | |
| SCHEMBL1319215 | 0.81 | GPR139 (0.65) | ROCK1ROCK2PRKG1PRKACAGSK3A | |
| SCHEMBL29342884 | 0.81 | ROCK2 (0.62) | ROCK1ROCK2PRKG1PRKACAGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216796-A1 | N-HYDROXY-NAPHTHALENE DICARBOXAMIDE AND N-HYDROXY-BIPHENYL-DICARBOXAMIDE COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | KATTAR SOLOMON | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216796-A1 | N-HYDROXY-NAPHTHALENE DICARBOXAMIDE AND N-HYDROXY-BIPHENYL-DICARBOXAMIDE COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | BRDT, AADAC, ACIN1 | ROCK1 4393/4885ROCK2 4323/4885PRKG1 4658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.