SCHEMBL30239031

SCHEMBL30239031

NCc1cccc(N2C=NCC2)c1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PRMT6 Q96LA8 2/20 0.44
NCF1 P14598 1/20 0.41
LMNA P02545 1/20 0.40
PNMT P11086 1/20 0.39
ENPP2 Q13822 1/20 0.39
LOXL2 Q9Y4K0 2/20 0.38
KLKB1 P03952 2/20 0.37
AGXT P21549 3/20 0.37
ATM Q13315 1/20 0.34
F10 P00742 1/20 0.34
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28945107 1.00 PRMT6 (0.44) PRMT6NCF1LMNAPNMTENPP2
SCHEMBL30239523 1.00 PRMT6 (0.44) PRMT6NCF1LMNAPNMTENPP2
SCHEMBL30239452 0.84 LOXL2 (0.39) PRMT6NCF1LOXL2F10
SCHEMBL28945126 0.84 LOXL2 (0.39) PRMT6NCF1LOXL2F10
SCHEMBL27905277 0.79 ADRA2C (0.47) LMNAAGXT
Hydrochloric Acid SCHEMBL28021391 0.78 ADRA2C (0.46) LMNAAGXT
SCHEMBL27810311 0.76 MEN1 (0.43) LMNA
SCHEMBL27662780 0.74 AGXT (0.56) PRMT6NCF1LMNAPNMTENPP2
SCHEMBL105023 0.74 SIGMAR1 (0.41) LMNA
SCHEMBL6272216 0.74 SIGMAR1 (0.41) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110234630-B Phenylimidazolines having aminomethyl groups Compound or salt thereof and process for producing the same 三菱瓦斯化学株式会社 2023-02-03 CN disclosed