SCHEMBL30241543

SCHEMBL30241543

COc1cccc2c1c(NS(=O)(=O)c1ccc(Cl)s1)nn2Cc1cccc(CNC(=O)C(C)(C)O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CCR4 P51679 20/20 1.00
CCR5 P51681 1/20 1.00
FFAR4 Q5NUL3 1/20 1.00
SLCO1B1 Q9Y6L6 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL358731 1.00 CCR4 (1.00) CCR4CCR5FFAR4SLCO1B1
SCHEMBL30241535 1.00 CCR4 (1.00) CCR4CCR5FFAR4SLCO1B1
SCHEMBL30241522 1.00 CCR4 (1.00) CCR4CCR5FFAR4SLCO1B1
SCHEMBL22653557 0.99 CCR4 (0.98) CCR4CCR5FFAR4SLCO1B1
SCHEMBL30522123 0.99 CCR4 (0.98) CCR4CCR5FFAR4SLCO1B1
Potassium SCHEMBL30522127 0.99 CCR4 (0.98) CCR4CCR5FFAR4SLCO1B1
SCHEMBL22653553 0.99 CCR4 (0.98) CCR4CCR5FFAR4SLCO1B1
SCHEMBL358278 0.95 CCR4 (0.90) CCR4CCR5FFAR4SLCO1B1
SCHEMBL186736 0.94 CCR4 (1.00) CCR4CCR5FFAR4SLCO1B1
SCHEMBL10235136 0.93 CCR4 (0.86) CCR4CCR5FFAR4SLCO1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230172912-A1 COMPOUNDS FOR TREATING PNEUMONIA, SEPSIS, AND CORONAVIRUS INFECTION HEIDELBERG IMMUNOTHERAPEUTICS GMBH (DE) 2023-06-08 US disclosed
EP-4132525-A1 COMPOUNDS FOR TREATING PNEUMONIA, SEPSIS, AND CORONAVIRUS INFECTION Heidelberg ImmunoTherapeutics GmbH (DE) 2023-02-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230172912-A1 COMPOUNDS FOR TREATING PNEUMONIA, SEPSIS, AND CORONAVIRUS INFECTION CCR5, CXCR3, CCL5 CCR4 15/4885CCR5 1/4885FFAR4 419/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.