Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 20/20 | 1.00 |
| ▸ | CCR5 | P51681 | 1/20 | 1.00 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 1.00 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30241535 | 1.00 | CCR4 (1.00) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL30241543 | 1.00 | CCR4 (1.00) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL30241522 | 1.00 | CCR4 (1.00) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL22653557 | 0.99 | CCR4 (0.98) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL30522123 | 0.99 | CCR4 (0.98) | CCR4CCR5FFAR4SLCO1B1 | |
| Potassium SCHEMBL30522127 | 0.99 | CCR4 (0.98) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL22653553 | 0.99 | CCR4 (0.98) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL358278 | 0.95 | CCR4 (0.90) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL186736 | 0.94 | CCR4 (1.00) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL10235136 | 0.93 | CCR4 (0.86) | CCR4CCR5FFAR4SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401270-B1 | PYRAZOLE DERIVATIVES USED AS CCR4 RECEPTOR ANTAGONISTS | GLAXO GROUP LTD (GB) | 2013-10-16 | — | — | EP | claimed |
| US-8357716-B2 | Pyrazole derivatives used as CCR4 receptor antagonists | GLAXO GROUP LIMITED (GB) | 2013-01-22 | — | — | US | claimed |
| US-8304446-B2 | Compounds | GLAXO GROUP LIMITED (GB) | 2012-11-06 | — | — | US | claimed |
| US-20120015932-A1 | Pyrazole Derivatives Used as CCR4 Receptor Antagonists | GLAXO GROUP LIMITED (GB) | 2012-01-19 | — | — | US | claimed |
| US-20100216860-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2010-08-26 | — | — | US | claimed |
| EP-3908601-B1 | COMPOSITIONS FOR TREATING CANCER | OMEROS CORP (US) | 2025-12-24 | — | — | EP | disclosed |
| EP-3738962-B1 | SALTS OF A COMPOUND AND USE THEREOF | MEDSPRING INTERNATIONAL LTD (CN) | 2023-08-02 | — | — | EP | disclosed |
| EP-3738962-B1 | SALTS OF A COMPOUND AND USE THEREOF | MEDSPRING INTERNATIONAL LTD (CN) | 2023-08-02 | — | — | EP | disclosed |
| US-20230172912-A1 | COMPOUNDS FOR TREATING PNEUMONIA, SEPSIS, AND CORONAVIRUS INFECTION | HEIDELBERG IMMUNOTHERAPEUTICS GMBH (DE) | 2023-06-08 | — | — | US | disclosed |
| CN-110028501-B | Compound and preparation method and application thereof | 迈德欣国际有限公司 | 2022-02-22 | — | — | CN | disclosed |
| CN-113893220-A | Nasal mucosal dosage form and uses thereof | 迈德欣国际有限公司 | 2022-01-07 | — | — | CN | disclosed |
| CN-113727999-A | Methods and compositions for treating cancer | 奥默罗斯公司 | 2021-11-30 | — | — | CN | disclosed |
| US-8304446-B2 | Compounds | GLAXO GROUP LIMITED (GB) | 2012-11-06 | — | — | US | disclosed |
| US-8304446-B2 | Compounds | GLAXO GROUP LIMITED (GB) | 2012-11-06 | — | — | US | disclosed |
| US-20120015932-A1 | Pyrazole Derivatives Used as CCR4 Receptor Antagonists | GLAXO GROUP LIMITED (GB) | 2012-01-19 | — | — | US | disclosed |
| US-20120015932-A1 | Pyrazole Derivatives Used as CCR4 Receptor Antagonists | GLAXO GROUP LIMITED (GB) | 2012-01-19 | — | — | US | disclosed |
| WO-2010097395-A1 | PYRAZOLE DERIVATIVES USED AS CCR4 RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2010-09-02 | — | — | WO | disclosed |
| US-20100216860-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2010-08-26 | — | — | US | disclosed |
| US-20100216860-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2010-08-26 | — | — | US | disclosed |
| US-20100216860-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015932-A1 | Pyrazole Derivatives Used as CCR4 Receptor Antagonists | CCR4, CCR3, CCR1 | CCR4 1/4885CCR5 8/4885FFAR4 73/4885 |
| US-20230172912-A1 | COMPOUNDS FOR TREATING PNEUMONIA, SEPSIS, AND CORONAVIRUS INFECTION | CCR5, CXCR3, CCL5 | CCR4 15/4885CCR5 1/4885FFAR4 419/4885 |
| US-20100216860-A1 | NOVEL COMPOUNDS | CYP3A4, CYP3A43, ABCG2 | CCR4 3196/4885CCR5 1719/4885FFAR4 2349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.