Biphenyl

Biphenyl

SCHEMBL3024307

O=C(SC(=O)c1ccccc1)c1ccccc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.50
KMO O15229 1/20 0.50
NPC1 O15118 1/20 0.50
CTDSP1 Q9GZU7 1/20 0.50
MAPT P10636 5/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
CES1 P23141 3/20 0.48
CES2 O00748 2/20 0.48
ALDH1A1 P00352 2/20 0.48
TSHR P16473 2/20 0.48
DAO P14920 1/20 0.48
NAPRT Q6XQN6 1/20 0.48
HDAC8 Q9BY41 1/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
LMNA P02545 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.44
CYP3A4 P08684 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4453783 0.92 CES1 (0.55) MAPTSMN1; SMN2CES1CES2ALDH1A1
SCHEMBL528366 0.90 CES1 (0.52) MAPTSMN1; SMN2CES1CES2ALDH1A1
SCHEMBL28013116 0.90 CES1 (0.52) MAPTSMN1; SMN2CES1CES2ALDH1A1
Phosphine SCHEMBL28389655 0.90 CES1 (0.52) MAPTSMN1; SMN2CES1CES2ALDH1A1
SCHEMBL1271166 0.78 CES1 (0.50) MAPTSMN1; SMN2CES1CES2ALDH1A1
SCHEMBL12263018 0.78 CA2 (0.54) MAPTSMN1; SMN2CES1CES2ALDH1A1
SCHEMBL28005968 0.78 TDP1 (0.54) MAPTSMN1; SMN2CES1CES2ALDH1A1
SCHEMBL36053 0.78 CES1 (0.46) MAPTSMN1; SMN2CES1CES2ALDH1A1
SCHEMBL238059 0.76 CES1 (0.44) MAPTSMN1; SMN2CES1CES2ALDH1A1
Benzophenone SCHEMBL260937 0.76 ALDH1A1 (0.82) RAB9AKMONPC1CTDSP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006082103-A2 NOVEL CATIONlC COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME DSM IP ASSETS B.V. (NL) 2006-08-10 WO claimed
CN-106716251-A Photosensitive resin composition, dry film and cured coating film thereof, and printed wiring board using same 太阳油墨制造株式会社 2017-05-24 CN disclosed
US-8871133-B2 Method and composition for reducing waste in photo-imaging applications DSM IP ASSETS B.V. (NL) 2014-10-28 US disclosed
US-20120178020-A1 METHOD AND COMPOSITION FOR REDUCING WASTE IN PHOTO-IMAGING APPLICATIONS DSM IP ASSETS (NL) 2012-07-12 US disclosed
US-20100201019-A1 Method and composition for reducing waste in photo-imaging applications DSM IP ASSETS B.V. 2010-08-12 US disclosed
US-20100001437-A1 METHOD AND COMPOSITION FOR REDUCING WASTE IN PHOTO-IMAGING APPLICATIONS DSM IP ASSETS B.V. (NL) 2010-01-07 US disclosed
WO-2006082103-A2 NOVEL CATIONlC COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME DSM IP ASSETS B.V. (NL) 2006-08-10 WO disclosed
US-4337289-A PHOTOPOLYMERIZED INK ON A SUBSTRATE HAVING A WATER SOLUBLE RELEASE COATING REED KENNETH J 1982-06-29 US disclosed
US-4326005-A Dry release transfer Reed, Kenneth James (GB) 1982-04-20 US disclosed
US-4286008-A THE DESIGN LAYER COMPRISING A FLEXIBLE PHOTOPOLYMERIZED ACRYLIC INK BEING RESISTANT TO THE STRESS OF THE MECHANICAL FORCE OF A STYLUS E. T. MARLER LIMITED (GB) 1981-08-25 US disclosed
US-4216019-A FOR SCREEN PRINTING; PHOTOPOLYMERIZATION Reed, Kenneth James (GB) 1980-08-05 US disclosed
EP-0003689-A1 Dry-release transfer and method of producing such a transfer Reed, Kenneth James (GB) 1979-08-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100201019-A1 Method and composition for reducing waste in photo-imaging applications PARG, PHOSPHO1, FLNA RAB9A 882/4885KMO 1803/4885NPC1 1094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.