Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3026394 | 0.93 | POLB (0.36) | POLBMAPK1TDP1ABCB1 | |
| SCHEMBL3026477 | 0.87 | — | — | |
| SCHEMBL3029793 | 0.86 | POLB (0.32) | POLBMAPK1TDP1 | |
| SCHEMBL718787 | 0.85 | POLB (0.31) | POLBMAPK1 | |
| SCHEMBL3019892 | 0.84 | POLB (0.31) | POLBMAPK1 | |
| SCHEMBL711739 | 0.84 | ABCB1 (0.33) | POLBMAPK1ABCB1 | |
| SCHEMBL3024604 | 0.80 | POLB (0.31) | POLBMAPK1 | |
| SCHEMBL3030375 | 0.79 | LMNA (0.35) | POLBMAPK1 | |
| SCHEMBL3026647 | 0.79 | — | — | |
| SCHEMBL3023746 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100189656-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100189656-A1 | CONTRAST AGENTS | IPO4, TPO, IPO11 | POLB 2343/4885MAPK1 2071/4885TDP1 2002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.