Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.78 |
| ▸ | FLT1 | P17948 | 2/20 | 0.78 |
| ▸ | RET | P07949 | 1/20 | 0.78 |
| ▸ | CDK2 | P24941 | 1/20 | 0.78 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.78 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.78 |
| ▸ | KIF5B | P33176 | 1/20 | 0.78 |
| ▸ | KDR | P35968 | 1/20 | 0.78 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.78 |
| ▸ | EGFR | P00533 | 11/20 | 0.77 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.76 |
| ▸ | FBP1 | P09467 | 5/20 | 0.74 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.73 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.73 |
| ▸ | RAF1 | P04049 | 1/20 | 0.64 |
| ▸ | BRAF | P15056 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30249695 | 0.88 | KDR (1.00) | FGFR1FLT1RETCDK2PIK3R1 | |
| SCHEMBL1180103 | 0.88 | KDR (1.00) | FGFR1FLT1RETCDK2PIK3R1 | |
| SCHEMBL29435034 | 0.88 | KDR (1.00) | FGFR1FLT1RETCDK2PIK3R1 | |
| Hydrochloric Acid SCHEMBL30433676 | 0.86 | NOD1 (1.00) | FGFR1FLT1RETCDK2PIK3R1 | |
| SCHEMBL2100996 | 0.86 | EGFR (0.77) | EGFRFBP1ERBB2ERBB4 | |
| SCHEMBL4477758 | 0.86 | EGFR (0.77) | RETKDREGFRFBP1ERBB2 | |
| SCHEMBL7119658 | 0.85 | FBP1 (1.00) | EGFRFBP1ERBB2ERBB4 | |
| SCHEMBL5606140 | 0.85 | FBP1 (1.00) | EGFRFBP1ERBB2ERBB4RAF1 | |
| SCHEMBL3008965 | 0.85 | FBP1 (1.00) | EPHB2KDREGFRFBP1ERBB2 | |
| Hydrochloric Acid SCHEMBL3258223 | 0.84 | EGFR (0.75) | EGFRFBP1ERBB2ERBB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070123537-A1 | Quinazoline derivatives for the treatment of herpesviral infections | GPC BIOTECH AG (DE) | 2007-05-31 | — | — | US | claimed |
| EP-1673346-A1 | QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF HERPESVIRAL INFECTIONS | GPC Biotech AG (DE) | 2006-06-28 | — | — | EP | claimed |
| WO-2005040125-A1 | QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF HERPESVIRAL INFECTIONS | GPC BIOTECH AG (DE) | 2005-05-06 | — | — | WO | claimed |
| US-20070123537-A1 | Quinazoline derivatives for the treatment of herpesviral infections | GPC BIOTECH AG (DE) | 2007-05-31 | — | — | US | disclosed |
| EP-1673346-A1 | QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF HERPESVIRAL INFECTIONS | GPC Biotech AG (DE) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005040125-A1 | QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF HERPESVIRAL INFECTIONS | GPC BIOTECH AG (DE) | 2005-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123537-A1 | Quinazoline derivatives for the treatment of herpesviral infections | IRF3, PML, TPMT | FGFR1 2809/4885FLT1 2348/4885RET 2776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.