SCHEMBL30250211

C[C@@H](OC(C)(C)C)[C@H](NC(=O)CNC(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)C(C)(C)NC(=O)[C@H](Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](COC(C)(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)O)[C@@H](C)OC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	OPRD1	P41143	10/20	0.36

▸	OPRM1	P35372	4/20	0.36

▸	OPRK1	P41145	4/20	0.36

▸	PSEN1	P49768	8/20	0.36

▸	PSEN2	P49810	8/20	0.36

▸	APH1B	Q8WW43	8/20	0.36

▸	NCSTN	Q92542	8/20	0.36

▸	APH1A	Q96BI3	8/20	0.36

▸	PSENEN	Q9NZ42	8/20	0.36

▸	CCKAR	P32238	6/20	0.35

▸	CCKBR	P32239	6/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30343346	0.97	PSEN1 (0.36)	OPRD1OPRM1OPRK1PSEN1PSEN2
SCHEMBL30524340	0.96	PSEN1 (0.37)	OPRD1OPRM1OPRK1PSEN1PSEN2
SCHEMBL30524338	0.94	PSEN1 (0.38)	OPRD1OPRM1OPRK1PSEN1PSEN2
SCHEMBL30437554	0.93	PSEN1 (0.37)	OPRD1OPRM1OPRK1PSEN1PSEN2
SCHEMBL30384193	0.93	ACE (0.37)	PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL34461946	0.91	REN (0.39)	OPRD1CCKARCCKBR
SCHEMBL30863518	0.91	PSEN1 (0.39)	OPRD1OPRM1OPRK1PSEN1PSEN2
SCHEMBL34461945	0.88	REN (0.40)	OPRD1CCKARCCKBR
SCHEMBL31002038	0.88	OPRM1 (0.38)	OPRD1OPRM1OPRK1PSEN1PSEN2
SCHEMBL31094168	0.87	REN (0.38)	OPRD1CCKARCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4146249-A1	IMPROVED PROCESS FOR THE PREPARATION OF SEMAGLUTIDE	Neuland Laboratories Ltd (IN)	2023-03-15	—	—	EP	disclosed