SCHEMBL30384193

SCHEMBL30384193

C[C@@H](OC(C)(C)C)[C@H](NC(=O)CNC(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)C(C)(C)NC(=O)[C@H](Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ACE P12821 1/20 0.37
▸ PSEN1 P49768 9/20 0.37
▸ PSEN2 P49810 9/20 0.37
▸ APH1B Q8WW43 9/20 0.37
▸ NCSTN Q92542 9/20 0.37
▸ APH1A Q96BI3 9/20 0.37
▸ PSENEN Q9NZ42 9/20 0.37
▸ CTSS P25774 2/20 0.37
▸ NMBR P28336 1/20 0.37
▸ CTSL P07711 1/20 0.37
▸ CTSB P07858 1/20 0.37
▸ CTSK P43235 1/20 0.37
▸ SIRT2 Q8IXJ6 1/20 0.36
▸ REN P00797 2/20 0.35
▸ AKT1 P31749 1/20 0.35
▸ PSMB1 P20618 1/20 0.35
▸ PSMB8 P28062 1/20 0.35
▸ PSMB9 P28065 1/20 0.35
▸ PSMB5 P28074 1/20 0.35
▸ PSMB10 P40306 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30524340 0.95 PSEN1 (0.37) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL30863518 0.95 PSEN1 (0.39) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL30343346 0.93 PSEN1 (0.36) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL30250211 0.93 OPRD1 (0.36) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL31614440 0.92 REN (0.41) ACERENPSMB1PSMB8PSMB9
SCHEMBL30385359 0.92 PTPN1 (0.38) NMBRSIRT2
SCHEMBL30524338 0.91 PSEN1 (0.38) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL30437554 0.90 PSEN1 (0.37) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL30384691 0.89 NMBR (0.40) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL30384822 0.87 PTPN1 (0.44) NMBRSIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230133716-A1 PREPARATION METHOD FOR SEMAGLUTIDE Shenzhen JYMed Technology Co., Ltd. (CN) 2023-05-04 — — US claimed
US-20250188115-A1 PROCESS FOR PREPARING A GLUCAGON-LIKE PEPTIDE CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2025-06-12 — — US disclosed
US-20230133716-A1 PREPARATION METHOD FOR SEMAGLUTIDE Shenzhen JYMed Technology Co., Ltd. (CN) 2023-05-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230133716-A1 PREPARATION METHOD FOR SEMAGLUTIDE GCG, GLP1R, DPP7 ACE 1831/4885PSEN1 198/4885PSEN2 327/4885
US-20250188115-A1 PROCESS FOR PREPARING A GLUCAGON-LIKE PEPTIDE GLP1R, IAPP, GCG ACE 2075/4885PSEN1 1218/4885PSEN2 937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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