SCHEMBL30863518

SCHEMBL30863518

C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)C(C)(C)NC(=O)[C@H](Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)NC(=O)OC(C)(C)C)[C@@H](C)OC(C)(C)C)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ PSEN1 P49768 13/20 0.39
▸ PSEN2 P49810 13/20 0.39
▸ APH1B Q8WW43 13/20 0.39
▸ NCSTN Q92542 13/20 0.39
▸ APH1A Q96BI3 13/20 0.39
▸ PSENEN Q9NZ42 13/20 0.39
▸ OPRM1 P35372 4/20 0.37
▸ OPRD1 P41143 4/20 0.37
▸ OPRK1 P41145 4/20 0.37
▸ PSMB1 P20618 1/20 0.36
▸ PSMB8 P28062 1/20 0.36
▸ PSMB9 P28065 1/20 0.36
▸ PSMB5 P28074 1/20 0.36
▸ PSMB10 P40306 1/20 0.36
▸ PSMB2 P49721 1/20 0.36
▸ REN P00797 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30384193 0.95 ACE (0.37) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL30524340 0.94 PSEN1 (0.37) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL30384691 0.92 NMBR (0.40) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL30343346 0.92 PSEN1 (0.36) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL30250211 0.91 OPRD1 (0.36) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL30524338 0.90 PSEN1 (0.38) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL31614440 0.89 REN (0.41) OPRD1PSMB1PSMB8PSMB9PSMB5
SCHEMBL30437554 0.89 PSEN1 (0.37) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL30385359 0.87 PTPN1 (0.38) —
SCHEMBL30107533 0.86 REN (0.41) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4602064-B1 METHOD OF MANUFACTURING A PEPTIDE WITH A LYSINE DERIVATIVE BACHEM HOLDING AG (CH) 2026-05-13 — — EP disclosed
EP-4602064-A1 METHOD OF MANUFACTURING A PEPTIDE WITH A LYSINE DERIVATIVE Bachem Holding AG (CH) 2025-08-20 — — EP disclosed
WO-2025078040-A1 LYSINE SALT AND METHOD OF MANUFACTURING A LYSINE DERIVATIVE BACHEM HOLDING AG (CH) 2025-04-17 — — WO disclosed
WO-2024079043-A1 METHOD OF MANUFACTURING A PEPTIDE WITH A LYSINE DERIVATIVE BACHEM HOLDING AG (CH) 2024-04-18 — — WO disclosed
Send feedback