SCHEMBL30250367

SCHEMBL30250367

CC(C)(C)OC(=O)CC[C@H](NC(=O)C(C)(C)NC(=O)[C@H](Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)NC(=O)OC(C)(C)C)C(=O)NCC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ NMBR P28336 1/20 0.42
▸ SIRT2 Q8IXJ6 12/20 0.41
▸ CTSS P25774 3/20 0.38
▸ CTSK P43235 2/20 0.38
▸ CTSL P07711 1/20 0.38
▸ CTSB P07858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30384919 0.92 SIRT2 (0.44) NMBRSIRT2CTSSCTSKCTSL
SCHEMBL30665993 0.91 NMBR (0.44) NMBRSIRT2CTSSCTSKCTSL
SCHEMBL30384691 0.90 NMBR (0.40) NMBRSIRT2
SCHEMBL30277394 0.89 NMBR (0.44) NMBRSIRT2CTSS
SCHEMBL29427178 0.88 NMBR (0.51) NMBRSIRT2CTSSCTSKCTSL
SCHEMBL29427176 0.88 NMBR (0.51) NMBRSIRT2CTSSCTSKCTSL
SCHEMBL12981253 0.86 CTSS (0.35) CTSSCTSKCTSLCTSB
SCHEMBL31614316 0.84 NMBR (0.38) NMBRSIRT2
SCHEMBL18367552 0.83 SIRT2 (0.49) NMBRSIRT2CTSSCTSKCTSL
SCHEMBL30120772 0.83 SIRT2 (0.49) NMBRSIRT2CTSSCTSKCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119080911-B Semex lattice Synthesis method of lupeptide 中肽生化有限公司 2025-03-07 — — CN claimed
CN-119080911-A Semex lattice Synthesis method of lupeptide 中肽生化有限公司 2024-12-06 — — CN claimed
US-20230220036-A1 IMPROVED PROCESS FOR THE PREPARATION OF SEMAGLUTIDE NEULAND LABORATORIES LTD (IN) 2023-07-13 — — US claimed
EP-4146249-A1 IMPROVED PROCESS FOR THE PREPARATION OF SEMAGLUTIDE Neuland Laboratories Ltd (IN) 2023-03-15 — — EP claimed
CN-119080911-B Semex lattice Synthesis method of lupeptide 中肽生化有限公司 2025-03-07 — — CN disclosed
CN-119080911-A Semex lattice Synthesis method of lupeptide 中肽生化有限公司 2024-12-06 — — CN disclosed
CN-116693653-B Preparation method for large-scale production of somalupeptide 杭州湃肽生化科技有限公司 2023-10-31 — — CN disclosed
CN-116693653-A Preparation method for large-scale production of somalupeptide 杭州湃肽生化科技有限公司 2023-09-05 — — CN disclosed
US-20230220036-A1 IMPROVED PROCESS FOR THE PREPARATION OF SEMAGLUTIDE NEULAND LABORATORIES LTD (IN) 2023-07-13 — — US disclosed
EP-4146249-A1 IMPROVED PROCESS FOR THE PREPARATION OF SEMAGLUTIDE Neuland Laboratories Ltd (IN) 2023-03-15 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230220036-A1 IMPROVED PROCESS FOR THE PREPARATION OF SEMAGLUTIDE GCG, OGDH, ABAT NMBR 1574/4885SIRT2 3006/4885CTSS 1837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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