Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23885108 | 1.00 | L3MBTL1 (0.42) | L3MBTL1KMT2APTGS2ALDH1A1MEN1 | |
| SCHEMBL10625596 | 0.87 | KMT2A (0.52) | L3MBTL1KMT2AALDH1A1MEN1JAK2 | |
| SCHEMBL2338360 | 0.80 | PTGS2 (0.50) | KMT2APTGS2ALDH1A1MEN1RAB9A | |
| SCHEMBL20050944 | 0.79 | HDAC1 (0.52) | L3MBTL1KMT2AALDH1A1JAK2TP53 | |
| SCHEMBL31312589 | 0.79 | MAP2K1 (0.36) | L3MBTL1ALDH1A1JAK2TP53MAPT | |
| SCHEMBL15569990 | 0.79 | PDK1 (0.55) | L3MBTL1KMT2APTGS2JAK2MAPT | |
| SCHEMBL20560179 | 0.79 | KMT2A (0.43) | KMT2APTGS2ALDH1A1MEN1RAB9A | |
| SCHEMBL4607513 | 0.78 | ALB (0.49) | L3MBTL1KMT2AALDH1A1MEN1JAK2 | |
| SCHEMBL4607670 | 0.77 | L3MBTL1 (0.47) | L3MBTL1KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL22262468 | 0.76 | MAPT (0.48) | L3MBTL1KMT2AALDH1A1MEN1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705296-A1 | HETEROARYLINDOLE INHIBITORS OF APOL-1 | OmniAB, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024242846-A1 | HETEROARYLINDOLE INHIBITORS OF APOL-1 | OMNIAB, INC. (US) | 2024-11-28 | — | — | WO | disclosed |
| EP-4125914-A1 | PYRROLOPYRIMIDINE AMINES AS COMPLEMENT INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2023-02-08 | — | — | EP | disclosed |