Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.33 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24028007 | 0.72 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ATDP1TSHR | |
| SCHEMBL28947161 | 0.69 | ERN1 (0.42) | ALDH1A1MEN1KMT2ATDP1TSHR | |
| SCHEMBL15621301 | 0.68 | AR (0.47) | ALDH1A1MEN1KMT2ATDP1PTGS2 | |
| SCHEMBL1663012 | 0.68 | ACHE (0.48) | ALDH1A1MEN1KMT2ATDP1TSHR | |
| SCHEMBL910073 | 0.68 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2ATDP1TSHR | |
| SCHEMBL31227003 | 0.68 | ACHE (0.48) | ALDH1A1MEN1KMT2ATDP1TSHR | |
| SCHEMBL1133242 | 0.68 | MYC (0.34) | ALDH1A1MEN1KMT2ATDP1TSHR | |
| SCHEMBL15543777 | 0.65 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2ATDP1MAPT | |
| SCHEMBL19682803 | 0.65 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ATDP1MAPT | |
| SCHEMBL21196268 | 0.65 | MEN1 (0.33) | ALDH1A1MEN1KMT2ATDP1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4149928-A1 | IMIDAZOLE 3-OXIDE DERIVATIVE BASED ACSS2 INHIBITORS AND METHODS OF USE THEREOF | Metabomed Ltd (IL) | 2023-03-22 | — | — | EP | disclosed |