Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 7/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 7/20 | 0.48 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.43 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23121408 | 0.92 | GPR119 (0.48) | DDB1CRBNLIPE | |
| SCHEMBL30257613 | 0.89 | DDB1 (0.52) | DDB1CRBNALKPDE3BPDE3A | |
| SCHEMBL25079570 | 0.89 | DDB1 (0.52) | DDB1CRBNALKPDE3BPDE3A | |
| SCHEMBL23142790 | 0.86 | DDB1 (0.48) | DDB1CRBN | |
| SCHEMBL31255309 | 0.85 | DDB1 (0.49) | DDB1CRBNALKPDE3BPDE3A | |
| SCHEMBL30257619 | 0.85 | DDB1 (0.62) | DDB1CRBNLIPEKMT2AMEN1 | |
| SCHEMBL22119507 | 0.83 | DDB1 (0.59) | DDB1CRBNTSHRKMT2AMEN1 | |
| SCHEMBL26266557 | 0.83 | ALDH1A1 (0.58) | DDB1CRBNMAPK1TPSAB1TPSD1 | |
| SCHEMBL25079332 | 0.82 | TPSAB1 (0.61) | DDB1CRBNMAPK1TPSAB1TPSD1 | |
| SCHEMBL30501294 | 0.81 | MEN1 (0.55) | DDB1CRBNKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023531-A1 | ESTROGEN RECEPTOR DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2023-02-23 | — | — | WO | disclosed |