Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 11/20 | 0.38 |
| ▸ | NPC1 | O15118 | 10/20 | 0.38 |
| ▸ | MITF | O75030 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22834914 | 0.84 | RAB9A (0.43) | ABCB1RAB9ANPC1MITFTP53 | |
| SCHEMBL22842977 | 0.82 | ABCB1 (0.40) | ABCB1RAB9ANPC1MITFTP53 | |
| SCHEMBL22842963 | 0.81 | GRIN2B (0.41) | GSK3BDYRK1ARAB9ANPC1TP53 | |
| SCHEMBL30258809 | 0.81 | GRIN2B (0.41) | GSK3BDYRK1ARAB9ANPC1TP53 | |
| Trifluoroacetic Acid SCHEMBL22834915 | 0.79 | RIPK1 (0.37) | ABCB1RAB9ANPC1MITFTP53 | |
| SCHEMBL22842998 | 0.78 | NPC1 (0.58) | ABCB1RAB9ANPC1MITFTP53 | |
| SCHEMBL22842960 | 0.76 | SORT1 (0.48) | ABCB1GSK3BDYRK1ARAB9ANPC1 | |
| SCHEMBL22842964 | 0.76 | IRAK4 (0.46) | ABCB1GSK3BDYRK1ARAB9ANPC1 | |
| SCHEMBL22842959 | 0.74 | SYK (0.45) | GSK3BDYRK1ARAB9ANPC1KMT2A | |
| SCHEMBL29598205 | 0.74 | SYK (0.45) | GSK3BDYRK1ARAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230087118-A1 | IMIDAZO[1,2-a]PYRIDINYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | BIOGEN MA INC. | 2023-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230087118-A1 | IMIDAZO[1,2-a]PYRIDINYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | IRAK4, IRAK2, IRAK1 | ABCB1 1849/4885GSK3B 693/4885DYRK1A 841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.