Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 5/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | KHK | P50053 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15972115 | 1.00 | CYP11B2 (0.44) | CYP11B2CYP11B1CHEK1HTTKMT2A | |
| SCHEMBL30217691 | 0.75 | HTT (0.54) | CYP11B2CYP11B1CHEK1HTTKMT2A | |
| SCHEMBL459834 | 0.75 | CHEK1 (0.37) | CYP11B2CYP11B1CHEK1HTTKMT2A | |
| SCHEMBL31200432 | 0.75 | CHRNB2 (0.40) | CYP11B2CYP11B1CHEK1HTTKMT2A | |
| SCHEMBL17486279 | 0.75 | CYP11B2 (0.37) | CYP11B2CYP11B1CHEK1HTTKMT2A | |
| SCHEMBL29658015 | 0.75 | CYP11B2 (0.37) | CYP11B2CYP11B1CHEK1HTTKMT2A | |
| SCHEMBL322329 | 0.75 | HTT (0.54) | CYP11B2CYP11B1CHEK1HTTKMT2A | |
| SCHEMBL1164261 | 0.75 | ALDH1A1 (0.53) | CYP11B2CYP11B1CHEK1HTTKMT2A | |
| SCHEMBL29904603 | 0.75 | ALDH1A1 (0.53) | CYP11B2CYP11B1CHEK1HTTKMT2A | |
| SCHEMBL17403581 | 0.75 | CHRNB2 (0.40) | CYP11B2CYP11B1CHEK1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230063457-A1 | DNA-PK INHIBITING COMPOUNDS | PROVINCIAL HEALTH SERVICES AUTHORITY (CA) | 2023-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230063457-A1 | DNA-PK INHIBITING COMPOUNDS | DCK, POLK, ERCC2 | CYP11B2 1696/4885CYP11B1 1446/4885CHEK1 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.