Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 7/20 | 0.62 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.54 |
| ▸ | PRKACB | P22694 | 1/20 | 0.54 |
| ▸ | GHSR | Q92847 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30452484 | 0.94 | NPBWR1 (0.57) | NPBWR1PRKACBGHSR | |
| SCHEMBL30452155 | 0.91 | NPBWR1 (0.61) | NPBWR1IL23RPRKACB | |
| SCHEMBL30259958 | 0.89 | GHSR (0.55) | NPBWR1GHSR | |
| SCHEMBL30492107 | 0.86 | PRKACB (0.57) | NPBWR1PRKACBGHSR | |
| SCHEMBL31073545 | 0.83 | GHSR (0.55) | NPBWR1GHSR | |
| SCHEMBL30452073 | 0.83 | ECE1 (0.58) | GHSR | |
| SCHEMBL29493330 | 0.83 | GHSR (0.60) | IL23RGHSR | |
| SCHEMBL29485117 | 0.83 | PRKACB (0.55) | NPBWR1PRKACBGHSR | |
| SCHEMBL30259946 | 0.82 | GHSR (0.51) | NPBWR1GHSR | |
| SCHEMBL29511199 | 0.82 | NPBWR1 (0.57) | NPBWR1IL23RPRKACBGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203096-A1 | EPHA4 TARGETING COMPOUNDS AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-06-29 | — | — | US | disclosed |
| EP-4139326-A1 | EPHA4 TARGETING COMPOUNDS AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-03-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203096-A1 | EPHA4 TARGETING COMPOUNDS AND METHODS OF USE THEREOF | EPHA4, EPHA1, EPHA5 | NPBWR1 4413/4885IL23R 2714/4885PRKACB 3808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.