Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 3/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 1/20 | 0.57 |
| ▸ | ACE | P12821 | 2/20 | 0.56 |
| ▸ | PLAU | P00749 | 1/20 | 0.55 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.55 |
| ▸ | GHSR | Q92847 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5795834 | 0.92 | LTA4H (0.60) | PPARGLTA4HACEGHSR | |
| SCHEMBL19051488 | 0.89 | PPARG (0.66) | PPARGACE | |
| SCHEMBL30452484 | 0.88 | NPBWR1 (0.57) | GHSR | |
| SCHEMBL30051248 | 0.85 | LTA4H (0.67) | ECE1LTA4HACEGHSR | |
| SCHEMBL30052824 | 0.85 | LTA4H (0.67) | ECE1LTA4HACEGHSR | |
| SCHEMBL5500900 | 0.85 | PPARG (0.63) | PPARGACE | |
| SCHEMBL15692399 | 0.84 | LTA4H (0.66) | ECE1LTA4HACE | |
| SCHEMBL15692374 | 0.84 | LTA4H (0.66) | ECE1LTA4HACE | |
| SCHEMBL29405776 | 0.84 | GHSR (0.61) | GHSR | |
| SCHEMBL7251382 | 0.84 | BMP1 (0.56) | PPARGGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203096-A1 | EPHA4 TARGETING COMPOUNDS AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203096-A1 | EPHA4 TARGETING COMPOUNDS AND METHODS OF USE THEREOF | EPHA4, EPHA1, EPHA5 | ECE1 576/4885PPARG 3428/4885LTA4H 634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.