Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.75 |
| ▸ | HTT | P42858 | 1/20 | 0.75 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.60 |
| ▸ | PHGDH | O43175 | 1/20 | 0.59 |
| ▸ | NAMPT | P43490 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | RAF1 | P04049 | 1/20 | 0.57 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24107872 | 1.00 | LMNA (0.75) | LMNAHTTCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL24107788 | 0.89 | PHGDH (0.71) | LMNAHTTCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL204698 | 0.83 | CYP1A1 (0.90) | LMNACYP1A1CYP1A2CYP1B1SMN1; SMN2 | |
| SCHEMBL24107520 | 0.83 | PHGDH (0.54) | LMNAHTTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL24107632 | 0.82 | ADORA3 (0.69) | HTTCYP1A1CYP1A2CYP1B1ALDH1A1 | |
| SCHEMBL30292503 | 0.82 | CYP1A1 (0.66) | LMNAHTTCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL24107596 | 0.82 | CYP1A1 (0.66) | LMNAHTTCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL24107533 | 0.81 | L3MBTL1 (0.54) | LMNAHTTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL24107521 | 0.80 | ALDH1A1 (0.63) | LMNAHTTCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL25287793 | 0.80 | LMNA (0.90) | LMNACYP1A2SMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161921-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | Anima Biotech Inc. (US) | 2023-04-12 | — | — | EP | disclosed |
| CN-115916776-A | Collagen 1 translation inhibitors and methods of use thereof | 艾尼莫生物科技公司 | 2023-04-04 | — | — | CN | disclosed |