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SCHEMBL30264992

SCHEMBL30264992

N=C(N)NCCC[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=O)NC(=O)CN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ GHSR Q92847 1/20 0.53
▸ MC4R P32245 2/20 0.53
▸ IL23R Q5VWK5 9/20 0.52
▸ KISS1R Q969F8 4/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30264785 0.98 GHSR (0.55) GHSRMC4RIL23RKISS1R
SCHEMBL30264795 0.92 NPY1R (0.52) GHSRMC4RIL23RKISS1R
SCHEMBL30264864 0.91 GHSR (0.58) GHSRMC4RKISS1R
SCHEMBL30264769 0.91 IL23R (0.53) MC4RIL23RKISS1R
SCHEMBL30264577 0.90 MC4R (0.52) GHSRMC4RIL23RKISS1R
SCHEMBL30264858 0.90 GHSR (0.51) GHSRMC4RIL23RKISS1R
SCHEMBL30264918 0.90 IL23R (0.54) MC4RIL23RKISS1R
SCHEMBL29485122 0.89 GHSR (0.54) GHSRMC4RKISS1R
SCHEMBL30264871 0.89 QRFPR (0.49) —
SCHEMBL31184496 0.89 KISS1R (0.53) MC4RKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4392072-A1 MC4R AGONIST PEPTIDES The Regents Of The University Of Michigan (US) 2024-07-03 — — EP disclosed
WO-2023028538-A1 MC4R AGONIST PEPTIDES THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2023-03-02 — — WO disclosed
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