SCHEMBL30264785

SCHEMBL30264785

N=C(N)NCCC[C@H](NC(=O)CN)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ GHSR Q92847 2/20 0.55
▸ MC4R P32245 2/20 0.55
▸ IL23R Q5VWK5 7/20 0.54
▸ KISS1R Q969F8 4/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30264992 0.98 GHSR (0.53) GHSRMC4RIL23RKISS1R
SCHEMBL30264577 0.93 MC4R (0.52) GHSRMC4RIL23RKISS1R
SCHEMBL29485122 0.91 GHSR (0.54) GHSRMC4RKISS1R
SCHEMBL30264755 0.91 GHSR (0.61) GHSRMC4RKISS1R
SCHEMBL31184496 0.91 KISS1R (0.53) MC4RKISS1R
SCHEMBL29511055 0.91 KISS1R (0.53) MC4RKISS1R
SCHEMBL29476104 0.91 KISS1R (0.53) MC4RKISS1R
SCHEMBL29476415 0.91 KISS1R (0.53) MC4RKISS1R
SCHEMBL30786983 0.91 KISS1R (0.53) MC4RKISS1R
SCHEMBL30264643 0.90 IL23R (0.54) MC4RIL23RKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240391954-A1 MC4R AGONIST PEPTIDES THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-11-28 — — US disclosed
EP-4392072-A1 MC4R AGONIST PEPTIDES The Regents Of The University Of Michigan (US) 2024-07-03 — — EP disclosed
WO-2023028538-A1 MC4R AGONIST PEPTIDES THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2023-03-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240391954-A1 MC4R AGONIST PEPTIDES MC4R, MC3R, MC5R GHSR 24/4885MC4R 1/4885IL23R 359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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