Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 2/20 | 0.36 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10950701 | 0.77 | TSHR (0.42) | TSHRALDH1A1LMNAGSRNPC1 | |
| SCHEMBL3325718 | 0.77 | TSHR (0.50) | TSHRALDH1A1LMNATDP1KMT2A | |
| SCHEMBL5716680 | 0.77 | ALDH1A1 (0.50) | TSHRALDH1A1LMNATDP1KMT2A | |
| SCHEMBL10567133 | 0.75 | LMNA (0.46) | TSHRALDH1A1LMNAGSRNPC1 | |
| SCHEMBL8510918 | 0.75 | LMNA (0.46) | TSHRALDH1A1LMNAGSRNPC1 | |
| SCHEMBL6281430 | 0.75 | LMNA (0.46) | TSHRALDH1A1LMNAGSRNPC1 | |
| SCHEMBL146897 | 0.75 | LMNA (0.46) | TSHRALDH1A1LMNAGSRNPC1 | |
| SCHEMBL5604305 | 0.74 | CYP1A2 (0.50) | TSHRALDH1A1NPC1TDP1KMT2A | |
| SCHEMBL1150553 | 0.73 | LMNA (0.44) | TSHRALDH1A1LMNAGSRNPC1 | |
| SCHEMBL11696138 | 0.73 | LMNA (0.44) | TSHRALDH1A1LMNAGSRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 472 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478045-A | Method for synthesizing nitrobenzoic acid by one-step oxidation of nitrobenzyl chloride | 南昌大学 | 2023-07-25 | — | — | CN | claimed |
| CN-107417542-B | A kind of 2,2 '-diamino bibenzyl preparation methods | 甘肃皓天医药科技有限责任公司 | 2019-11-08 | — | — | CN | claimed |
| CN-107075105-B | Moisture-curable, polyether carbonic ester containing alkoxysilyl | 科思创德国股份有限公司 | 2019-09-13 | — | — | CN | claimed |
| CN-107056730-B | A kind of synthetic method and its application of bupropion hydrochloride sustained release tablets impurity isomers | 浙江普洛家园药业有限公司 | 2019-05-24 | — | — | CN | claimed |
| CN-109796458-A | A kind of synthetic method of 1,8- diazabicyclo | 淄博鸿润新材料有限公司 | 2019-05-24 | — | — | CN | claimed |
| CN-109678746-A | A kind of anxiolytic Lorazepam intermediate simplicity synthesis technology | 南京诺希生物科技有限公司 | 2019-04-26 | — | — | CN | claimed |
| CN-106008221-B | A kind of synthetic method of adjacent nitro benzyl chloride | 四川福思达生物技术开发有限责任公司 | 2019-04-19 | — | — | CN | claimed |
| CN-106008348-B | A kind of method of synthesizing pyrazole kresoxim-methyl intermediate | 四川福思达生物技术开发有限责任公司 | 2019-03-05 | — | — | CN | claimed |
| CN-108892648-A | A kind of Lizakuputan benzoate intermediate process for solid phase synthesis | 山东贵邦药业有限公司 | 2018-11-27 | — | — | CN | claimed |
| CN-106831814-B | A kind of thieno [3,2-d] miazines HIV-1 reverse transcriptase inhibitor and its preparation method and application | 山东大学 | 2018-11-23 | — | — | CN | claimed |
| US-5565602-A | REACTING A HYDROCARBYL CHLORIDE WITH A CARBONYL SULFIDE AND AMINE IN PRESENCE OF A BASIC CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1996-10-15 | — | — | US | claimed |
| US-5126485-A | Inhibition of dehalogenation during catalytic hydrogenation | RHONE-POULENC CHIMIE (FR) | 1992-06-30 | — | — | US | claimed |
| EP-0285294-B1 | PHENYLHYDRAZONE DERIVATIVE OF OXAMIDE AND HERBICIDAL COMPOSITION CONTAINING THE SAME | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-07-03 | — | — | EP | claimed |
| EP-0360552-A2 | The preparation of nitroesters via the reaction of nitroparaffins with cyanoformates | W.R. Grace & Co.-Conn. (US) | 1990-03-28 | — | — | EP | claimed |
| EP-0170090-B1 | SUBSTITUTED BENZOATE ESTER PRODRUG DERIVATIVES OF 3-HYDROXYMORPHINANS, INTERMEDIATES THERETO, AND PROCESSES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-09-27 | — | — | EP | claimed |
| US-4866204-A | OXIDATION WITH METAL ACETYLACETONATES, PORPYRINS OR PHTHALOCYANINE CATALYSTS | NOBEL CHEMICALS AB (SE) | 1989-09-12 | — | — | US | claimed |
| EP-0285294-A1 | Phenylhydrazone derivative of oxamide and herbicidal composition containing the same | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-10-05 | — | — | EP | claimed |
| US-4283565-A | REACTING A BENZYL HALIDE WITH A FORMATE, CONTACTING WITH AN ALCOHOL TO TRANSESTERIFY | DYNAMIT NOBEL AG (DE) | 1981-08-11 | — | — | US | claimed |
| US-4151165-A | USING AN AROMATIC NITRO COMPOUND IN OXYGEN-FREE, AQUEOUS ENVIRONMENT | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1979-04-24 | — | — | US | claimed |
| US-4059610-A | Process for preparing isocyanic acid derivatives | KAO SOAP CO., LTD. (JA) | 1977-11-22 | — | — | US | claimed |