Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 12/20 | 0.63 |
| ▸ | VEGFA | P15692 | 11/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL277774 | 1.00 | EGLN1 (0.63) | EGLN1VEGFAHDAC1LMNACXCR4 | |
| SCHEMBL15314769 | 0.86 | VEGFA (0.46) | EGLN1VEGFAHDAC1LMNACXCR4 | |
| SCHEMBL12598822 | 0.79 | VEGFA (0.84) | EGLN1VEGFA | |
| SCHEMBL21667235 | 0.78 | VEGFA (0.79) | EGLN1VEGFALMNAKDM4EALDH1A1 | |
| SCHEMBL12598821 | 0.77 | EGLN1 (1.00) | EGLN1VEGFA | |
| SCHEMBL12598820 | 0.77 | EGLN1 (0.70) | EGLN1VEGFA | |
| SCHEMBL15314767 | 0.77 | VEGFA (0.68) | EGLN1VEGFAKDM4E | |
| SCHEMBL1772403 | 0.76 | VEGFA (1.00) | EGLN1VEGFAHDAC1 | |
| SCHEMBL278429 | 0.76 | VEGFA (1.00) | EGLN1VEGFAHDAC1 | |
| SCHEMBL273125 | 0.75 | VEGFA (0.70) | EGLN1VEGFAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116018136-A | Hypoxia-inducible factor prolyl hydroxylase inhibitors for the treatment of aging-related disorders | 百爱及生物医药公司 | 2023-04-25 | — | — | CN | disclosed |
| EP-4142721-A1 | HYPOXIA-INDUCIBLE FACTOR PROLYL HYDROXYLASE INHIBITORS FOR TREATING AGING-RELATED CONDITIONS | Bioage Labs, Inc. (US) | 2023-03-08 | — | — | EP | disclosed |