Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 5/20 | 0.46 |
| ▸ | ACE | P12821 | 6/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29720744 | 0.90 | ITGB1 (0.42) | TRHRACE | |
| SCHEMBL29630592 | 0.90 | TRHR (0.46) | TRHR | |
| SCHEMBL29591738 | 0.90 | TRHR (0.46) | TRHR | |
| SCHEMBL31409131 | 0.88 | TRHR (0.44) | TRHRACEACE2TSHR | |
| SCHEMBL30356636 | 0.86 | APLNR (0.40) | TRHRACEACE2 | |
| SCHEMBL30769779 | 0.85 | TRHR (0.37) | TRHR | |
| SCHEMBL30356635 | 0.85 | APLNR (0.39) | TRHRACEACE2 | |
| SCHEMBL29802223 | 0.85 | TSHR (0.44) | TRHRACEACE2TSHR | |
| SCHEMBL30800721 | 0.83 | TRHR (0.49) | TRHR | |
| SCHEMBL30769690 | 0.83 | CTSL (0.39) | TRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12329799-B2 | Peptidyl inhibitors of calcineurin-NFAT interaction | OHIO STATE INNOVATION FOUNDATION (US) | 2025-06-17 | — | — | US | disclosed |
| US-20240033318-A1 | PEPTIDYL INHIBITORS OF CALCINEURIN-NFAT INTERACTION | OHIO STATE INNOVATION FOUNDATION | 2024-02-01 | — | — | US | disclosed |
| US-11576946-B2 | Peptidyl inhibitors of calcineurin-NFAT interaction | OHIO STATE INNOVATION FOUNDATION (US) | 2023-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12329799-B2 | Peptidyl inhibitors of calcineurin-NFAT interaction | CHP1, NFATC1, PPP3R1 | TRHR 2889/4885ACE 2182/4885ACE2 1902/4885 |
| US-20240033318-A1 | PEPTIDYL INHIBITORS OF CALCINEURIN-NFAT INTERACTION | CHP1, NFATC1, PPP3R1 | TRHR 2889/4885ACE 2182/4885ACE2 1902/4885 |
| US-11576946-B2 | Peptidyl inhibitors of calcineurin-NFAT interaction | CHP1, NFATC1, PPP3R1 | TRHR 2889/4885ACE 2182/4885ACE2 1902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.