Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 6/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.31 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22249306 | 1.00 | ADORA2A (0.34) | ADORA2AADORA1ADORA2BNAMPTHTR4 | |
| SCHEMBL22248970 | 0.92 | ADORA2A (0.34) | ADORA2AADORA1ADORA2BNAMPTHTR4 | |
| SCHEMBL30276436 | 0.92 | ADORA2A (0.34) | ADORA2AADORA1ADORA2BNAMPTHTR4 | |
| SCHEMBL22248467 | 0.90 | ADORA2A (0.33) | ADORA2AADORA1ADORA2BNAMPTHTR4 | |
| SCHEMBL30276375 | 0.90 | ADORA2A (0.33) | ADORA2AADORA1ADORA2BNAMPTHTR4 | |
| SCHEMBL30276406 | 0.90 | ADORA2A (0.34) | ADORA2AADORA1ADORA2BNAMPTHTR4 | |
| SCHEMBL22248972 | 0.90 | ADORA2A (0.33) | ADORA2AADORA1ADORA2BNAMPTHTR4 | |
| SCHEMBL30276609 | 0.90 | ADORA2A (0.33) | ADORA2AADORA1ADORA2BNAMPTHTR4 | |
| SCHEMBL22248422 | 0.88 | ROCK2 (0.36) | HTR4ROCK2ACACBCYP3A4CYP2D6 | |
| SCHEMBL22236020 | 0.88 | HTR4 (0.35) | HTR4ROCK2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230072397-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230072397-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | ADORA2A 4726/4885ADORA1 4564/4885ADORA2B 4703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.