Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.37 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30703391 | 0.77 | RAB9A (0.56) | MAPTPOLBCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL7366622 | 0.76 | ALDH1A1 (0.44) | MAPTPOLBCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL15729325 | 0.74 | MAPT (0.39) | MAPTPOLBALDH1A1GAA | |
| SCHEMBL23570177 | 0.71 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3KCNH2MAPT | |
| SCHEMBL2422435 | 0.71 | ALDH1A1 (0.45) | MAPTCYP2C9CYP2C19ERN1ALDH1A1 | |
| SCHEMBL6142808 | 0.71 | KMT2A (0.46) | TRPA1CYP2C9CYP2C19ALDH1A1GAA | |
| SCHEMBL21901796 | 0.70 | GRIN2B (0.44) | SLC6A2SLC6A4SLC6A3KCNH2POLB | |
| SCHEMBL5878669 | 0.70 | KDM4E (0.49) | MAPTALDH1A1TRIM24TRIM33 | |
| SCHEMBL4735355 | 0.70 | ADRB1 (0.41) | CARM1PRMT6ALDH1A1 | |
| SCHEMBL22809757 | 0.70 | ALDH1A1 (0.44) | SLC6A2SLC6A4SLC6A3KCNH2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703792-A | Tricyclic derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-02-17 | — | — | CN | disclosed |