SCHEMBL3027860

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4754814	1.00	CYP3A4 (0.44)	CYP3A4CYP1A2VCAM1MERTKKCNH2
	SCHEMBL3642514	0.89	CYP1A2 (0.39)	CYP3A4CYP1A2CYP2C9CYP2C19MAPT
	SCHEMBL13661733	0.88	CYP3A4 (0.45)	CYP3A4VCAM1MERTKKCNH2CYP2C9
	SCHEMBL1344613	0.85	CYP3A4 (0.55)	CYP3A4KCNH2CYP2C9CYP2C19EPAS1
	SCHEMBL4752770	0.85	CYP1A2 (0.41)	CYP1A2EPAS1MAPTVEGFANPC1
	SCHEMBL3038920	0.85	CYP1A2 (0.41)	CYP1A2EPAS1MAPTVEGFANPC1
	SCHEMBL3016476	0.84	VCAM1 (0.44)	CYP3A4VCAM1MERTKKCNH2EPAS1
	SCHEMBL1344803	0.83	CYP3A4 (0.47)	CYP3A4KCNH2CYP2C9CYP2C19EPAS1
	SCHEMBL4752470	0.83	CYP3A4 (0.49)	CYP3A4KCNH2CYP2C9CYP2C19EPAS1
	SCHEMBL16175755	0.83	CYP3A4 (0.61)	CYP3A4KCNH2CYP2C9CYP2C19EPAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.