Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | PLG | P00747 | 1/20 | 0.53 |
| ▸ | PLAU | P00749 | 1/20 | 0.53 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.53 |
| ▸ | KLK1 | P06870 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8205322 | 1.00 | F2 (0.53) | F2PLGPLAUKLKB1KLK1 | |
| Hydrochloric Acid SCHEMBL14118767 | 0.98 | F2 (0.52) | F2PLGPLAUKLKB1KLK1 | |
| SCHEMBL22062269 | 0.82 | CES2 (0.49) | F2PLGPLAUKLKB1KLK1 | |
| SCHEMBL30684671 | 0.80 | CA12 (0.59) | CES2CES1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL571295 | 0.80 | CA12 (0.59) | CES2CES1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13108706 | 0.80 | DGAT1 (0.62) | PRSS1DGAT1SMN1; SMN2ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL27783226 | 0.79 | CA12 (0.57) | CES2CES1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27804731 | 0.79 | CA12 (0.57) | CES2CES1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL437904 | 0.78 | DGAT1 (0.52) | F2DGAT1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13108721 | 0.78 | DGAT1 (0.52) | F2DGAT1NPC1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240299386-A1 | Novel imidazole derivatives having protein kinase inhibitory activity and uses thereof | INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS (KR) | 2024-09-12 | — | — | US | disclosed |
| WO-2023022463-A1 | NOVEL IMIDAZOLE DERIVATIVE HAVING INHIBITORY ACTIVITY ON PROTEIN PHOSPHORELATION AND USE THEREOF | 한양대학교 에리카산학협력단 | 2023-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240299386-A1 | Novel imidazole derivatives having protein kinase inhibitory activity and uses thereof | MAPKAPK3, MAPK3, MAP2K3 | F2 4559/4885PLG 4636/4885PLAU 4178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.