Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 7/20 | 0.46 |
| ▸ | DRD3 | P35462 | 4/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12489240 | 1.00 | FASN (0.46) | FASNDRD3DRD2PNMTSLC6A4 | |
| SCHEMBL1275908 | 0.78 | HTR2C (0.47) | DRD2PNMTHTR2CHTR2BHTR2A | |
| SCHEMBL737193 | 0.78 | DPP4 (0.42) | HTR2CHTR2ASIGMAR1 | |
| SCHEMBL30508182 | 0.78 | PNMT (0.41) | PNMTSLC6A4HTR2CHTR2BHTR2A | |
| SCHEMBL3745717 | 0.78 | AVPR1A (0.40) | FASNOPRM1SIGMAR1KDM1A | |
| Hydrochloric Acid SCHEMBL4985671 | 0.77 | AVPR1A (0.39) | FASNOPRM1SIGMAR1KDM1A | |
| SCHEMBL4046452 | 0.75 | SIGMAR1 (0.36) | SIGMAR1CYP3A4CYP2D6CYP2C9ALOX15 | |
| SCHEMBL22648506 | 0.75 | TDP2 (0.39) | PNMTHTR2CHTR2BKCNH2HTR2A | |
| SCHEMBL2817157 | 0.74 | SLC6A4 (0.46) | DRD3SLC6A4SLC6A2HTR2CADRA1A | |
| SCHEMBL30187749 | 0.74 | SLC6A4 (0.46) | DRD3SLC6A4SLC6A2HTR2CADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116139138-A | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-110177551-B | Heterocyclic modulators of lipid synthesis | 3-V生物科学股份有限公司 | 2023-02-17 | — | — | CN | disclosed |