Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 1/20 | 0.34 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.34 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28974169 | 0.83 | KDM1A (0.36) | TEAD1TEAD4TEAD2CDK8OPRM1 | |
| SCHEMBL28974193 | 0.81 | RET (0.33) | TEAD1TEAD4TEAD2OPRM1PARP1 | |
| SCHEMBL28976439 | 0.80 | PARP1 (0.31) | TEAD1TEAD4TEAD2OPRM1PARP1 | |
| SCHEMBL28976913 | 0.80 | PARP1 (0.31) | TEAD1TEAD4TEAD2OPRM1PARP1 | |
| SCHEMBL28976466 | 0.72 | PARP1 (0.33) | OPRM1PARP1PARP2 | |
| SCHEMBL28976914 | 0.72 | KDM1A (0.31) | PARP1PARP2 | |
| SCHEMBL24758185 | 0.72 | CRHR1 (0.33) | — | |
| SCHEMBL28976316 | 0.71 | NPC1 (0.35) | TEAD1TEAD4TEAD2OPRM1 | |
| SCHEMBL22312633 | 0.70 | KDM4E (0.35) | LMNASMN1; SMN2 | |
| SCHEMBL28974185 | 0.69 | KDM1A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143195-A1 | IMIDAZOPYRIDAZINES AS MODULATORS OF IL-17 | Janssen Pharmaceutica NV (BE) | 2023-03-08 | — | — | EP | disclosed |