Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.30 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.30 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28974169 | 0.83 | KDM1A (0.36) | PARP1PARP2OPRM1TEAD1TEAD4 | |
| SCHEMBL28974193 | 0.81 | RET (0.33) | PARP1PARP2OPRM1TEAD1TEAD4 | |
| SCHEMBL30281182 | 0.80 | TEAD1 (0.34) | PARP1PARP2OPRM1TEAD1TEAD4 | |
| SCHEMBL28976439 | 0.80 | PARP1 (0.31) | PARP1PARP2OPRM1TEAD1TEAD4 | |
| SCHEMBL28976914 | 0.72 | KDM1A (0.31) | PARP1PARP2 | |
| SCHEMBL28976466 | 0.70 | PARP1 (0.33) | PARP1PARP2OPRM1 | |
| SCHEMBL4177951 | 0.68 | KDM4E (0.39) | — | |
| SCHEMBL28976927 | 0.68 | PARP1 (0.33) | PARP1PARP2OPRM1 | |
| SCHEMBL28976940 | 0.68 | PARP1 (0.32) | PARP1PARP2 | |
| SCHEMBL24758185 | 0.67 | CRHR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115884810-A | Imidazopyridazines as IL-17 modulators | 詹森药业有限公司 | 2023-03-31 | — | — | CN | disclosed |