Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.36 |
| ▸ | GSK3A | P49840 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30281370 | 0.82 | EPHX2 (0.52) | EPHX2MAPTL3MBTL1JMJD6POLB | |
| Nitrous Acid SCHEMBL28864182 | 0.82 | L3MBTL1 (0.55) | EPHX2MAPTL3MBTL1JMJD6POLB | |
| SCHEMBL796410 | 0.81 | L3MBTL1 (0.60) | EPHX2MAPTL3MBTL1JMJD6POLB | |
| SCHEMBL2713663 | 0.80 | EPHX2 (0.52) | EPHX2MAPTL3MBTL1JMJD6POLB | |
| SCHEMBL30403546 | 0.80 | EPHX2 (0.52) | EPHX2MAPTL3MBTL1JMJD6POLB | |
| SCHEMBL31191107 | 0.77 | EPHX2 (0.53) | EPHX2MAPTL3MBTL1JMJD6POLB | |
| SCHEMBL27913659 | 0.77 | EPHX2 (0.50) | EPHX2MAPTL3MBTL1JMJD6POLB | |
| SCHEMBL13875980 | 0.77 | EPHX2 (0.50) | EPHX2MAPTL3MBTL1JMJD6POLB | |
| SCHEMBL28525630 | 0.76 | EPHX2 (0.45) | EPHX2L3MBTL1JMJD6GSK3BGSK3A | |
| SCHEMBL13890805 | 0.76 | EPHX2 (0.52) | EPHX2MAPTL3MBTL1JMJD6POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901646-A | Benzotriazine double oxide and pharmaceutical composition thereof | 杭州瑞臻医药有限公司 | 2022-08-12 | — | — | CN | disclosed |