Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TLR2 | O60603 | 2/20 | 0.47 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.46 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3036594 | 1.00 | LMNA (0.51) | LMNAALDH1A1TLR2PRKCAPRKCE | |
| SCHEMBL3028306 | 0.96 | ALDH1A1 (0.55) | LMNAALDH1A1TLR2PRKCAPRKCE | |
| SCHEMBL3030628 | 0.96 | ALDH1A1 (0.55) | LMNAALDH1A1TLR2PRKCAPRKCE | |
| SCHEMBL3034803 | 0.96 | ALDH1A1 (0.55) | LMNAALDH1A1TLR2PRKCAPRKCE | |
| SCHEMBL3027565 | 0.94 | ALDH1A1 (0.50) | LMNAALDH1A1TLR2PRKCAPRKCE | |
| SCHEMBL3392589 | 0.94 | ALDH1A1 (0.50) | LMNAALDH1A1TLR2PRKCAPRKCE | |
| SCHEMBL3392153 | 0.94 | ALDH1A1 (0.50) | LMNAALDH1A1TLR2PRKCAPRKCE | |
| SCHEMBL3037068 | 0.93 | LMNA (0.48) | LMNAALDH1A1TLR2LPAR3LPAR1 | |
| SCHEMBL3028631 | 0.93 | LMNA (0.48) | LMNAALDH1A1TLR2LPAR3LPAR1 | |
| SCHEMBL3028169 | 0.93 | LMNA (0.48) | LMNAALDH1A1TLR2LPAR3LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100202998-A1 | USE OF AT LEAST ONE LYSINE-DERIVED COMPOUND FOR THE CONDITIONING OF KERATINOUS FIBERS, COSMETIC COMPOSITION COMPRISING IT AND METHOD FOR CONDITIONING THE FIBERS | L'OREAL S.A. (FR) | 2010-08-12 | — | — | US | claimed |
| US-20100202998-A1 | USE OF AT LEAST ONE LYSINE-DERIVED COMPOUND FOR THE CONDITIONING OF KERATINOUS FIBERS, COSMETIC COMPOSITION COMPRISING IT AND METHOD FOR CONDITIONING THE FIBERS | L'OREAL S.A. (FR) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100202998-A1 | USE OF AT LEAST ONE LYSINE-DERIVED COMPOUND FOR THE CONDITIONING OF KERATINOUS FIBERS, COSMETIC COMPOSITION COMPRISING IT AND METHOD FOR CONDITIONING THE FIBERS | KRT18, DSG1, PLOD3 | LMNA 520/4885ALDH1A1 674/4885TLR2 280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.