Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 4/20 | 0.56 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.54 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.54 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CHUK | O15111 | 1/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.54 |
| ▸ | CDK1 | P06493 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | LTK | P29376 | 1/20 | 0.54 |
| ▸ | CDK8 | P49336 | 1/20 | 0.54 |
| ▸ | PRKX | P51817 | 1/20 | 0.54 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.54 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.54 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21640344 | 0.98 | ROCK2 (0.55) | ROCK2ROCK1GLAPKN2RPS6KA5 | |
| SCHEMBL1552756 | 0.84 | ULK1 (0.56) | ROCK2ROCK1GLAPKN2RPS6KA5 | |
| SCHEMBL30828553 | 0.83 | ROCK2 (0.76) | ROCK2ROCK1GLAPKN2RPS6KA5 | |
| SCHEMBL7520976 | 0.83 | ROCK2 (0.76) | ROCK2ROCK1GLAPKN2RPS6KA5 | |
| SCHEMBL1553389 | 0.83 | ROCK2 (0.61) | ROCK2ROCK1GLAPKN2RPS6KA5 | |
| SCHEMBL2297677 | 0.81 | HPGD (0.62) | GLATP53TSHRCLK4LMNA | |
| Hydrochloric Acid SCHEMBL27545321 | 0.81 | ROCK2 (0.73) | ROCK2ROCK1GLAPKN2RPS6KA5 | |
| SCHEMBL15531012 | 0.81 | KHK (0.40) | ROCK2ROCK1GLAPKN2RPS6KA5 | |
| Hydrochloric Acid SCHEMBL27414471 | 0.81 | ROCK2 (0.60) | ROCK2ROCK1GLAPKN2RPS6KA5 | |
| SCHEMBL15530710 | 0.80 | PKM (0.53) | TP53CDK2LMNAALDH1A1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703765-B | Substituted triazole derivative, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-115703765-A | Substituted triazole derivative, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2023-02-17 | — | — | CN | disclosed |