Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 6/20 | 0.60 |
| ▸ | KMO | O15229 | 1/20 | 0.60 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1135975 | 1.00 | ERN1 (0.60) | ERN1KMOPDK2HDAC8MEN1 | |
| Hydrochloric Acid SCHEMBL28646857 | 0.98 | ERN1 (0.59) | ERN1KMOPDK2HDAC8MEN1 | |
| Trifluoroacetic Acid SCHEMBL5067780 | 0.90 | PDK2 (0.57) | ERN1KMOPDK2HDAC8MEN1 | |
| SCHEMBL27876786 | 0.90 | SMN1; SMN2 (0.55) | ERN1KMOPDK2HDAC8MEN1 | |
| SCHEMBL12168605 | 0.90 | ERN1 (0.58) | ERN1KMOPDK2LMNA | |
| SCHEMBL18311613 | 0.87 | ERN1 (0.64) | ERN1PDK2MEN1KMT2AHSD17B2 | |
| SCHEMBL17795214 | 0.87 | ERN1 (0.60) | ERN1KMOPDK2CYP3A4MAP4K1 | |
| SCHEMBL28022357 | 0.85 | KMO (0.56) | ERN1KMOHDAC8MEN1KMT2A | |
| SCHEMBL12472078 | 0.84 | ERN1 (0.56) | ERN1PDK2CYP3A4MAP4K1HSD17B2 | |
| SCHEMBL12469445 | 0.84 | ERN1 (0.59) | ERN1PDK2CYP3A4MAP4K1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427409-B | Pyrimidine-4 (3H) -one derivatives as TRPV4 antagonists | 拉夸里亚创药株式会社 | 2025-02-25 | — | — | CN | claimed |
| CN-119192174-A | Novel biphenyl carboxylic FXR agonist, preparation method thereof and application thereof as medicine | 广东药科大学 | 2024-12-27 | — | — | CN | claimed |
| CN-117255792-A | Heteroaryl derivatives, process for preparing the same and pharmaceutical compositions comprising the same as active ingredient | 沃若诺伊公司 | 2023-12-19 | — | — | CN | claimed |
| CN-119677740-A | Tertiary amine substituted bicyclic compounds useful as T cell activators | 百时美施贵宝公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-115427409-B | Pyrimidine-4 (3H) -one derivatives as TRPV4 antagonists | 拉夸里亚创药株式会社 | 2025-02-25 | — | — | CN | disclosed |
| CN-119192174-A | Novel biphenyl carboxylic FXR agonist, preparation method thereof and application thereof as medicine | 广东药科大学 | 2024-12-27 | — | — | CN | disclosed |
| CN-115776890-A | TRPV4 inhibitors as therapeutic agents for eye diseases | 拉夸里亚创药株式会社 | 2023-03-10 | — | — | CN | disclosed |