SCHEMBL3028472

SCHEMBL3028472

CCCC(C)(O)C#CC(C)(C)O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28388451 0.92 ALDH1A1 (0.37) FDPSALDH1A1
SCHEMBL394131 0.92 ALDH1A1 (0.37) FDPSALDH1A1
SCHEMBL17061383 0.86 ALDH1A1 (0.37) ALDH1A1
SCHEMBL28044131 0.82 FDPS (0.32) FDPSALDH1A1
SCHEMBL28379125 0.79
SCHEMBL932689 0.79
SCHEMBL13256388 0.78
SCHEMBL3659091 0.78 TSHR (0.32)
SCHEMBL29138571 0.77 FDPS (0.31) FDPSALDH1A1
SCHEMBL11755098 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2569071-B1 METHOD FOR THE DIRECT ELUTION OF REACTIVE [18F]FLUORIDE FROM AN ANION EXCHANGE RESIN IN AN ORGANIC MEDIUM SUITABLE FOR RADIOLABELLING WITHOUT ANY EVAPORATION STEP BY THE USE OF ALKALIMETAL AND ALKALINE EARTH METAL CRYPTATES UNIV MUENCHEN TECH (DE) 2015-07-08 EP claimed
US-8491790-B2 Method for the direct elution of reactive 18F fluoride from an anion exchange resin in an organic medium suitable for radiolabelling without any evaporation step by the use of strong organic bases TRASIS S.A. (BE) 2013-07-23 US claimed
EP-2164590-B1 METHOD FOR THE DIRECT ELUTION OF REACTIVE 18F FLUORIDE FROM AN ANION EXCHANGE RESIN IN AN ORGANIC MEDIUM SUITABLE FOR RADIOLABELLING WITHOUT ANY EVAPORATION STEP BY THE USE OF STRONG ORGANIC BASES TRASIS S A (BE) 2013-03-06 EP claimed
US-20100196254-A1 METHOD FOR THE DIRECT ELUTION OF REACTIVE 18F FLUORIDE FROM AN ANION EXCHANGE RESIN IN AN ORGANIC MEDIUM SUITABLE FOR RADIOLABELLING WITHOUT ANY EVAPORATION STEP BY THE USE OF STRONG ORGANIC BASES TRASIS S.A. (BE) 2010-08-05 US claimed
EP-2164590-A1 METHOD FOR THE DIRECT ELUTION OF REACTIVE 18F FLUORIDE FROM AN ANION EXCHANGE RESIN IN AN ORGANIC MEDIUM SUITABLE FOR RADIOLABELLING WITHOUT ANY EVAPORATION STEP BY THE USE OF STRONG ORGANIC BASES Trasis S.A. (BE) 2010-03-24 EP claimed
EP-2062630-A1 Method for the direct elution of reactive 18F fluoride from an anion exchange resin in an organic medium by the use of strong organic bases Trasis S.A. (BE) 2009-05-27 EP claimed
WO-2009003251-A1 METHOD FOR THE DIRECT ELUTION OF REACTIVE 18F FLUORIDE FROM AN ANION EXCHANGE RESIN IN AN ORGANIC MEDIUM SUITABLE FOR RADIOLABELLING WITHOUT ANY EVAPORATION STEP BY THE USE OF STRONG ORGANIC BASES TRASIS S.A. (BE) 2009-01-08 WO claimed
US-11242314-B2 Synthesizing pet tracers using [F-18]sulfonyl fluoride as a source of [F-18]fluoride WASHINGTON UNIVERSITY (US) 2022-02-08 US disclosed
US-20170197912-A1 SYNTHESIZING PET TRACERS USING [F-18]SULFONYL FLUORIDE AS A SOURCE OF [F-18]FLUORIDE WASHINGTON UNIVERSITY (US) 2017-07-13 US disclosed
US-8491790-B2 Method for the direct elution of reactive 18F fluoride from an anion exchange resin in an organic medium suitable for radiolabelling without any evaporation step by the use of strong organic bases TRASIS S.A. (BE) 2013-07-23 US disclosed
EP-2164590-B1 METHOD FOR THE DIRECT ELUTION OF REACTIVE 18F FLUORIDE FROM AN ANION EXCHANGE RESIN IN AN ORGANIC MEDIUM SUITABLE FOR RADIOLABELLING WITHOUT ANY EVAPORATION STEP BY THE USE OF STRONG ORGANIC BASES TRASIS S A (BE) 2013-03-06 EP disclosed
US-20100196254-A1 METHOD FOR THE DIRECT ELUTION OF REACTIVE 18F FLUORIDE FROM AN ANION EXCHANGE RESIN IN AN ORGANIC MEDIUM SUITABLE FOR RADIOLABELLING WITHOUT ANY EVAPORATION STEP BY THE USE OF STRONG ORGANIC BASES TRASIS S.A. (BE) 2010-08-05 US disclosed
EP-2062630-A1 Method for the direct elution of reactive 18F fluoride from an anion exchange resin in an organic medium by the use of strong organic bases Trasis S.A. (BE) 2009-05-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170197912-A1 SYNTHESIZING PET TRACERS USING [F-18]SULFONYL FLUORIDE AS A SOURCE OF [F-18]FLUORIDE STX18, GPR119, SLC5A1 FDPS 979/4885ALDH1A1 2643/4885
US-11242314-B2 Synthesizing pet tracers using [F-18]sulfonyl fluoride as a source of [F-18]fluoride STX18, GPR119, SLC5A1 FDPS 979/4885ALDH1A1 2643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.