SCHEMBL490127

SCHEMBL490127

O=c1c2ccccc2oc2cc(Br)ccc12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.67
KDM4E B2RXH2 1/20 0.67
ALDH1A1 P00352 1/20 0.67
GLA P06280 1/20 0.67
CYP3A4 P08684 1/20 0.67
MAPT P10636 1/20 0.67
HPGD P15428 1/20 0.67
PGAM1 P18669 1/20 0.67
CASP1 P29466 1/20 0.67
CASP7 P55210 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
HSD17B10 Q99714 1/20 0.67
NPC1 O15118 5/20 0.58
RAB9A P51151 5/20 0.58
TTR P02766 2/20 0.58
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
L3MBTL1 Q9Y468 3/20 0.53
NMUR2 Q9GZQ4 2/20 0.52
TNKS O95271 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31397562 1.00 MAOA (0.67) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL30923496 0.90 CYP11B1 (0.54) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL17752292 0.90 CYP11B1 (0.54) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL30284875 0.89 MAOA (0.67) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL2592127 0.89 MAOA (0.67) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL29381559 0.88 AHR (0.59) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL259160 0.88 AHR (0.59) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL30593469 0.87 PIM1 (0.51) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL47040 0.87 PIM1 (0.51) MAOAKDM4EALDH1A1GLACYP3A4
SCHEMBL28114240 0.86 MAOA (0.58) MAOAKDM4EALDH1A1GLACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112961157-A Indolocarbazole-based organic luminescent material and preparation method and application thereof 电子科技大学 2021-06-15 CN claimed
CN-105884830-A Bipolar OLED (organic light-emitting diode) phosphorescence main body material and luminescent device containing material 中节能万润股份有限公司 2016-08-24 CN claimed
EP-4692093-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME Solus Advanced Materials Co., Ltd. (KR) 2026-02-11 EP disclosed
CN-119552596-A Packaging adhesive suitable for high-speed cigarette making machine equipment and preparation method thereof 郑州神火胶剂有限公司 2025-03-04 CN disclosed
CN-119143755-A Method for preparing racemate from enantiomers of non-nefarious ketone or intermediate 奥锐特药业股份有限公司 2024-12-17 CN disclosed
WO-2024205127-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 솔루스첨단소재 주식회사 2024-10-03 WO disclosed
CN-118255752-A Organic light-emitting compound with sandwich-like structure and organic electronic device 华南理工大学 2024-06-28 CN disclosed
CN-114249713-B Organic compound containing xanthone or thioxanthone structure and application thereof 江苏三月科技股份有限公司 2024-05-03 CN disclosed
US-11873294-B2 Compound containing anthrone and nitrogen-containing heterocycle and application in OLED devices JIANGSU SUNERA TECHNOLOGY CO., LTD. (CN) 2024-01-16 US disclosed
US-11873294-B2 Compound containing anthrone and nitrogen-containing heterocycle and application in OLED devices JIANGSU SUNERA TECHNOLOGY CO., LTD. (CN) 2024-01-16 US disclosed
US-11825741-B2 Organic compound, organic light emitting diode and organic light emitting device including the organic compound LG DISPLAY CO., LTD. (KR) 2023-11-21 US disclosed
WO-2007030089-A1 TRICYCLIC DELTA- OPIOID MODULATORS JANSSEN PHARMACEUTICA N.V. (BE) 2007-03-15 WO disclosed
WO-2006069275-A1 TRICYCLIC DELTA-OPIOID MODULATORS JANSSEN PHARMACEUTICA N.V. (BE) 2006-06-29 WO disclosed
WO-2006069277-A1 TRICYCLIC δ-OPIOID MODULATORS JANSSEN PHARMACEUTICA N.V. (BE) 2006-06-29 WO disclosed
US-20060135524-A1 Tricyclic delta-opioid modulators JANSSEN PHARMACEUTICA N.V. (BE) 2006-06-22 US disclosed
US-20060135522-A1 Tricyclic delta-opioid modulators CARSON JOHN R 2006-06-22 US disclosed
EP-1644373-A1 TRICYCLIC DELTA OPIOID MODULATORS JANSSEN PHARMACEUTICA N.V. (BE) 2006-04-12 EP disclosed
US-20060030585-A1 Tricyclic delta-opioid modulators JANSSEN PHARMACEUTICA N.V. (BE) 2006-02-09 US disclosed
WO-2005003131-A1 TRICYCLIC DELTA OPIOID MODULATORS JANSSEN PHARMACEUTICA N.V. (BE) 2005-01-13 WO disclosed
US-20050009860-A1 Tricyclic delta-opioid modulators JANSSEN PHARMACEUTICA, N.V. (BE) 2005-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060135524-A1 Tricyclic delta-opioid modulators OPRD1, OPRK1, OPRL1 MAOA 948/4885KDM4E 2174/4885ALDH1A1 1302/4885
US-11825741-B2 Organic compound, organic light emitting diode and organic light emitting device including the organic compound OCIAD2, OCIAD1, EML4 MAOA 334/4885KDM4E 2583/4885ALDH1A1 1076/4885
US-20050009860-A1 Tricyclic delta-opioid modulators OPRD1, OPRK1, OPRL1 MAOA 948/4885KDM4E 2174/4885ALDH1A1 1302/4885
US-20060030585-A1 Tricyclic delta-opioid modulators OPRD1, OPRK1, OPRL1 MAOA 948/4885KDM4E 2174/4885ALDH1A1 1302/4885
US-20060135522-A1 Tricyclic delta-opioid modulators OPRD1, OPRK1, OPRL1 MAOA 948/4885KDM4E 2174/4885ALDH1A1 1302/4885
US-11873294-B2 Compound containing anthrone and nitrogen-containing heterocycle and application in OLED devices NLRP1, OCIAD2, OCIAD1 MAOA 189/4885KDM4E 2723/4885ALDH1A1 3143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.