Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 4/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LAP3 | P28838 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ECE1 | P42892 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29833638 | 0.92 | ECE1 (0.47) | OPRD1OPRM1OPRK1MAPTALDH1A1 | |
| SCHEMBL7553789 | 0.91 | MAPT (0.53) | OPRD1OPRM1OPRK1MAPTALDH1A1 | |
| SCHEMBL7150981 | 0.91 | MAPT (0.53) | OPRD1OPRM1OPRK1MAPTALDH1A1 | |
| SCHEMBL29414403 | 0.90 | MAPT (0.49) | OPRD1OPRM1OPRK1MAPTALDH1A1 | |
| SCHEMBL30661446 | 0.89 | OPRD1 (0.53) | OPRD1OPRM1OPRK1MAPTALDH1A1 | |
| SCHEMBL30661448 | 0.89 | OPRD1 (0.53) | OPRD1OPRM1OPRK1MAPTALDH1A1 | |
| SCHEMBL24977 | 0.87 | ECE1 (0.46) | OPRD1OPRM1OPRK1ALDH1A1MEN1 | |
| SCHEMBL9657142 | 0.85 | ALDH1A1 (0.53) | MAPTALDH1A1LAP3MEN1LMNA | |
| SCHEMBL29544382 | 0.84 | MME (0.44) | OPRD1OPRM1OPRK1MAPTALDH1A1 | |
| SCHEMBL4803053 | 0.84 | ECE1 (0.43) | OPRD1OPRM1OPRK1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4673554-A1 | ASPARAGINYL PEPTIDE LIGASE-MEDIATED RADIOLABELLING OF SINGLE-DOMAIN ANTIBODIES | Nanyang Technological University (SG) | 2026-01-07 | — | — | EP | claimed |
| WO-2024181930-A1 | ASPARAGINYL PEPTIDE LIGASE-MEDIATED RADIOLABELLING OF SINGLE-DOMAIN ANTIBODIES | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2024-09-06 | — | — | WO | claimed |
| EP-4673554-A1 | ASPARAGINYL PEPTIDE LIGASE-MEDIATED RADIOLABELLING OF SINGLE-DOMAIN ANTIBODIES | Nanyang Technological University (SG) | 2026-01-07 | — | — | EP | disclosed |
| US-20250270610-A1 | Improving the Efficiency of PAL-Catalyzed Protein Ligation By A Cascade Enzymatic Scheme | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2025-08-28 | — | — | US | disclosed |
| CN-119563032-A | Detection composition and use thereof | 健达九州(北京)生物科技有限公司 | 2025-03-04 | — | — | CN | disclosed |
| EP-4499858-A1 | IMPROVING THE EFFICIENCY OF PAL-CATALYZED PROTEIN LIGATION BY A CASCADE ENZYMATIC SCHEME | Nanyang Technological University (SG) | 2025-02-05 | — | — | EP | disclosed |
| CN-119234043-A | PAL-catalytic protein ligation efficiency by cascade enzymatic method | 南洋理工大学 | 2024-12-31 | — | — | CN | disclosed |
| WO-2024181930-A1 | ASPARAGINYL PEPTIDE LIGASE-MEDIATED RADIOLABELLING OF SINGLE-DOMAIN ANTIBODIES | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2024-09-06 | — | — | WO | disclosed |
| US-20240263210-A1 | METHODS FOR ENZYMATIC PEPTIDE LIGATION | UNIV NANYANG TECH (SG) | 2024-08-08 | — | — | US | disclosed |
| EP-3515931-B1 | METHODS FOR ENZYMATIC PEPTIDE LIGATION | UNIV NANYANG TECH (SG) | 2024-05-01 | — | — | EP | disclosed |
| CN-117925757-A | Asparagine endopeptidase mediated polypeptide cyclization method and application thereof in phage display peptide library | 安徽大学 | 2024-04-26 | — | — | CN | disclosed |
| WO-2024017263-A1 | DETECTION COMPOSITION AND USE THEREOF | GENANS BIOTECHNOLOGY CO., LTD (CN) | 2024-01-25 | — | — | WO | disclosed |
| CN-109790205-B | Method for enzymatic peptide ligation | 南洋理工大学 | 2024-01-16 | — | — | CN | disclosed |
| US-20230365656-A1 | A FUSION PROTEIN | THE UNIVERSITY OF QUEENSLAND (NZ) | 2023-11-16 | — | — | US | disclosed |
| US-11795488-B2 | Methods for enzymatic peptide ligation | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2023-10-24 | — | — | US | disclosed |
| WO-2023191726-A1 | IMPROVING THE EFFICIENCY OF PAL-CATALYZED PROTEIN LIGATION BY A CASCADE ENZYMATIC SCHEME | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2023-10-05 | — | — | WO | disclosed |
| US-20230128192-A1 | METHODS FOR ENZYMATIC PEPTIDE LIGATION | UNIV NANYANG TECH (SG) | 2023-04-27 | — | — | US | disclosed |
| EP-4161944-A1 | A FUSION PROTEIN | The University of Queensland (AU) | 2023-04-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250270610-A1 | Improving the Efficiency of PAL-Catalyzed Protein Ligation By A Cascade Enzymatic Scheme | QPCT, GLUL, QPCTL | OPRD1 4451/4885OPRM1 4619/4885OPRK1 4447/4885 |
| US-20240263210-A1 | METHODS FOR ENZYMATIC PEPTIDE LIGATION | XPNPEP1, LIG1, NGLY1 | OPRD1 1670/4885OPRM1 1707/4885OPRK1 3380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.