Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGK1 | O00141 | 8/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CCR4 | P51679 | 2/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 2/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21545874 | 1.00 | SGK1 (0.35) | SGK1CYP2C9CYP2C19CCR4TDO2 | |
| SCHEMBL21545905 | 0.89 | CCR4 (0.38) | SGK1CYP2C9CYP2C19CCR4ALPL | |
| SCHEMBL30286524 | 0.89 | CCR4 (0.38) | SGK1CYP2C9CYP2C19CCR4ALPL | |
| SCHEMBL20344327 | 0.87 | PIK3CD (0.32) | SGK1CYP2C9CYP2C19CCR2 | |
| SCHEMBL20355182 | 0.84 | CCR2 (0.41) | SGK1CYP2C9CYP2C19CCR4ALPL | |
| SCHEMBL30286487 | 0.82 | SCN9A (0.42) | SGK1CYP2C9CYP2C19CCR4TDO2 | |
| SCHEMBL21545847 | 0.82 | SCN9A (0.42) | SGK1CYP2C9CYP2C19CCR4TDO2 | |
| SCHEMBL20354726 | 0.80 | SLC40A1 (0.44) | SGK1CYP2C19CCR4ALPLNR4A2 | |
| SCHEMBL20355390 | 0.80 | CCR4 (0.39) | SGK1CYP2C9CYP2C19CCR4TDO2 | |
| SCHEMBL30286500 | 0.80 | SLC40A1 (0.44) | SGK1CYP2C19CCR4ALPLNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-116283712-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116036078-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | disclosed |