Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 5/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 2/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.35 |
| ▸ | SGK1 | O00141 | 3/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21545905 | 1.00 | CCR4 (0.38) | CCR4NR4A2MEN1KMT2ACCR2 | |
| SCHEMBL30286456 | 0.89 | SGK1 (0.35) | CCR4NR4A2CCR2SGK1CYP2C9 | |
| SCHEMBL21545874 | 0.89 | SGK1 (0.35) | CCR4NR4A2CCR2SGK1CYP2C9 | |
| SCHEMBL20355182 | 0.86 | CCR2 (0.41) | CCR4NR4A2CCR2SGK1CYP2C9 | |
| SCHEMBL20354726 | 0.84 | SLC40A1 (0.44) | CCR4NR4A2CCR2SGK1CYP2C19 | |
| SCHEMBL30286500 | 0.84 | SLC40A1 (0.44) | CCR4NR4A2CCR2SGK1CYP2C19 | |
| SCHEMBL21545847 | 0.84 | SCN9A (0.42) | CCR4NR4A2CCR2SGK1CYP2C9 | |
| SCHEMBL30286487 | 0.84 | SCN9A (0.42) | CCR4NR4A2CCR2SGK1CYP2C9 | |
| SCHEMBL20355390 | 0.82 | CCR4 (0.39) | CCR4NR4A2MEN1KMT2ACCR2 | |
| SCHEMBL29560319 | 0.82 | CCR4 (0.39) | CCR4NR4A2MEN1KMT2ACCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-116283712-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116036078-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | disclosed |