Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 8/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SGK1 | O00141 | 4/20 | 0.35 |
| ▸ | CCR2 | P41597 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | ATIC | P31939 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20354793 | 1.00 | ACLY (0.40) | ACLYTSHRPOLBCASP6CTDSP1 | |
| SCHEMBL30286518 | 0.86 | ACLY (0.42) | ACLYSGK1CCR2CYP2C9CYP2C19 | |
| SCHEMBL20354889 | 0.86 | ACLY (0.42) | ACLYSGK1CCR2CYP2C9CYP2C19 | |
| SCHEMBL30286645 | 0.84 | ACLY (0.39) | ACLYSGK1CCR2CYP2C9CYP2C19 | |
| SCHEMBL20340319 | 0.84 | ACLY (0.39) | ACLYSGK1CCR2CYP2C9CYP2C19 | |
| SCHEMBL20354873 | 0.83 | SLC40A1 (0.37) | ACLYPOLBCASP6CTDSP1TDP1 | |
| SCHEMBL30286447 | 0.83 | SLC40A1 (0.37) | ACLYPOLBCASP6CTDSP1TDP1 | |
| SCHEMBL20339179 | 0.83 | ACLY (0.42) | ACLYTSHRPOLBCASP6CTDSP1 | |
| SCHEMBL20355214 | 0.82 | HSD11B1 (0.38) | ACLYSGK1CCR2CYP2C9CYP2C19 | |
| SCHEMBL20354859 | 0.82 | ACLY (0.38) | ACLYSGK1CCR2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-116283712-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116036078-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | disclosed |